Not exact matches
It involves the way an egg
cell is built and how information positioned during that construction
affects the
fate of the embryo.
Chi said that eliminating autophagy also
affected the
fate of such regulatory T
cells.
By determining how changes in gene expression
affect the
fate of glial
cells in mice, we hope to understand the key factors that govern neural
cell regeneration in the human brain.
These modifications of p53 are believed to fine tune p53 - dependent gene regulation and
cell fate decisions by
affecting p53 protein stability, DNA binding affinity and interactions between p53 and other transcription cofactors.
Understanding the conditions that cause these
cells to go off to different
fates may have a bearing on health problems such as ectopic pregnancy, which occurs when the embryo develops outside of the womb in about 1 of 60 pregnancies, or molar pregnancy, which is abnormal tissue growth within the uterus that
affects about 1 in every 1,000 pregnancies.
Aberrant regulation of the epigenetic information results in changes in
cell fate decisions, thereby
affecting development and tissue homeostasis, and ultimately leading to disease, such as cancer.