Sentences with phrase «affects cell fate decisions»
Not exact matches
These modifications of p53 are believed to fine tune p53 - dependent gene regulation and cell fate decisions by affecting p53 protein stability, DNA binding affinity and interactions between p53 and other transcription cofactors.
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Aberrant regulation of the epigenetic information results in changes in cell fate decisions, thereby affecting development and tissue homeostasis, and ultimately leading to disease, such as cancer.