CoQ10
affects cellular energy and health across a wide range of systems.
Not exact matches
The
affected mitochondria could no longer provide the synapses with enough
energy, which ultimately prevented the synapses from functioning — providing the first direct link between
cellular injury caused by amyloid protein and the characteristic breakdown of neuronal communication that occurs in Alzheimer's patients.
The diseases in question
affect mitochondria, which are
cellular energy producers that carry their own set of genes.
Aβ is believed to penetrate neuronal plasma membranes, where it leads to lipid peroxidation.10 It has also been implicated in deactivating a subunit of the pyruvate dehydrogenase complex, thereby inhibiting conversion of pyruvate to acetyl CoA and the eventual production of
cellular energy as ATP.32 Another way Aβ
affects glucose metabolism in the brain is that fragments of Aβ disrupt insulin signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant at synapses, so if the integrity of the synapse itself has been compromised, the receptors won't function effectively.
Research indicates that
cellular energy production is greatly
affected by what is supplied in the diet.
Mitochondrial damage further drains
cellular energy by creating a disproportionate need for repair, perpetuating a vicious cycle.21 Mitochondrial dysfunction can
affect immunity, digestion, cognition and any
energy - intensive system within the body and is a key component of many chronic illnesses.
The body is under constant danger of becoming acid, due to the very basic process of
energy production, by oxidizing (breaking down) carbohydrates into carbon dioxide and water, producing acidic residue (CO2), that needs to be disposed of through
cellular respiration, and then exhaled through the lungs (this is why the rate of breathing can directly
affect body's acid / alkaline balance).
However, an example of a factor that
affects the ability of your muscles to absorb oxygen would be the extent of the blood capillary distribution at your muscles (more blood capillaries means more surface area for oxygen absorption), and an example of a factor that
affects the ability of your muscles to use oxygen would be the mitochondrial density of your muscles (mitochondria are organelles in your cells that are primarily responsible for the
cellular respiration process that uses oxygen to create ATP
energy).