Sentences with phrase «affects different cells»

Not exact matches

In a new study, researchers at the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science examined how the interaction of two genomes in animal cells — the mitochondrial and nuclear genomes — interact to affect adaptation of the Atlantic killifish to different temperatures.

Since pseudouridine modifications may affect various RNA molecules in different types of normal and malignant cells, «our discoveries pave the way for future avenues of research aimed at exploring the role of pseudouridine in human development disease,» concludes Cristian Bellodi.

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

The group then ran dozens of microscopy tests with Dan Wagner, Rice associate professor of biochemistry and cell biology, to see how different formulations and amounts of biochar affected cell signaling.

These conditions are distinguished by the different types of brain nerve cells that are first affected and by the symptoms that first appear.

Different drug molecules make it possible to affect the function of these receptors and, consequently, to prevent cell activation and mediator release.

He and colleagues have determined what gives cholera bacteria their curved shape and whether it matters (a polymer protein, and it does matter; the curve makes it easier for cholera to cause disease), how different wavelengths of light affect movement of photosynthetic bacteria (red and green wavelengths encourage movement; blue light stops the microbes in their tracks), how bacteria coordinate cell division machinery and how photosynthetic bacteria's growth changes in light and dark.

Neurodegenerative diseases are caused by the death of neurons and other cells in the brain, with different diseases affecting different regions of the brain.

Folate deficiency can result in several different complications — the most important of these are neural tube defects (such as spina bifida, an abnormality of the spine and spinal cord) in babies and anemia (in which the number and function of red blood cells is affected leading to an inability of the blood to carry sufficient oxygen).

The inside back cover image of the Nov. 20, 2017 issue of Advanced Materials illustrates how ion migration in a hybrid perovskite crystal affects solar cell performance in different areas of the crystal.

Each of the four families had a distinct mutation that affected a different region of the CARD11 protein, but all the mutations had similar effects on T - cell signaling.

Researchers in this study used budding yeast, creating populations of cells with more than 10 million different randomised genomes, to investigate how genetic diversity affected resistance.

«This tells you that all the different types of stromal cells in breast tissue are affected by the GT198 mutation because they all come from a common progenitor cell.»

Using a technique that measures the response of the olfactory system to odours, the researchers showed that copper and nickel affect the ability of different cells to detect odours.

It's a protein chain that spans the cell membrane with complicated 3D folding - including 36 repeating «beads on a necklace» folds that can each be modified in different ways to affect the protein's overall function.

Secreted by certain brain cells, APOE is known to regulate cholesterol metabolism within the brain and can bind to A-beta peptides, suggesting that the different forms of the protein may affect whether and how toxic A-beta plaques form.

Samples of tumours from bowel cancer patients given different doses of resveratrol showed that even lower doses can get into cancer cells and potentially affect processes involved in tumour growth.

Researchers used data from different people's genotypes and metabolism to build personalized models that simulate how a drug will affect a particular set of cells in the body.

At Emory, the pause has halted not only the CEIRS project with the lab - attenuated PR8 strain, but also a research grant project headed by Anice Lowen that is looking at how the cell types targeted by two different influenza viruses affect their propensity to exchange genes.

This is clear from the fact that the third drug in the study, sodium nitroprusside, does not affect endothelial cells, but still produced different effects in the veins of black people and white people.

«We don't really understand how many of these chemicals work and interact at a very basic level in cells and in the body, so being able to know how they affect different people with different genetic variations is problematic at best,» she says.

A study led by scientists from Harvard Medical School reveals «hidden» variability in how tumor cells are affected by anticancer drugs, offering new insights on why patients with the same form of cancer can have different responses to a drug.

«Exosomes and exomeres also have different biophysical characteristics, such as stiffness and electric charge, that likely affect their behavior in the body,» said lead author Dr. Haiying Zhang, an assistant professor of cell and developmental biology in pediatrics at Weill Cornell Medicine.

Moreover, the team used the technique to shed light on how three different invasion - inhibiting drugs affect interactions between the parasites and red blood cells.

Studying cancer with single - cell technology will allow us to unlock the interactions between different types of cells in tumors — and monitor how these interactions change over time, affecting patients» outcomes.

Although these processes are affected by many different cell types within the tumour stroma, macrophages and other myeloid - derived cells are among the most important players.

We looked at the different molecular and cell properties they had, how different drugs affected each — essentially comparing and contrasting the two cell types.

To understand why skin cells in diverse parts of the body have different characteristics - how cells know their «positional identities» - a fact that guides the diagnosis and treatment of many skin diseases, Dr. Chang and his colleagues are seeking to define in molecular terms how the expression of different genes in stromal cells determines their ability to affect the development of skin cells.

To address this in cynomolgus macaques (Macaca fascicularis), Elizabeth Dietrich of the University of Washington studied how different versions of the restriction factor TRIMCyp (taken from cynomolgus macaques from different geographical areas) can affect the susceptibility of cultured cells to infection with HIV - 1 and HIV - 2.

This visualization shows tightly - packed DNA in a mouse cell's nucleus at different stages of development, seen here in a semi-triangular form as a mature nerve cell; in a roundish shape as a multipotent stem cell; in a more oval form as a neuronal progenitor; and as a more fragmented structure that shows how removing a specialized binding protein (HP1β knockout) affects the structure of the DNA - packing material, called heterochromatin, in a mature neuron.

Understanding the conditions that cause these cells to go off to different fates may have a bearing on health problems such as ectopic pregnancy, which occurs when the embryo develops outside of the womb in about 1 of 60 pregnancies, or molar pregnancy, which is abnormal tissue growth within the uterus that affects about 1 in every 1,000 pregnancies.

How the other great apes lost the cells remains unknown, but the researchers theorize genetic disruptions affecting the cells» migration to different parts of the brain, differentiation, or survival could have led to the loss.

Epigenetic modifications in bacteria, such as DNA methylation, have been shown to affect gene regulation, thereby generating cells that are isogenic but with distinctly different phenotypes.

My research is framed within the Wellcome Trust consortium on the archaeal origins of eukaryotic cell organization (http://evocyt.com/), which includes a diverse group of researchers studying the evolution of eukaryotic machinery from different points of view — e.g. how do specific cellular systems work in different lineages, and how did that affect the origin of the eukaryotic cell plan?

First, demonstration of the possibility of modeling different diseases affecting adult cells using a single platform has answered one of the most pressing questions in the human iPS cell — disease modeling field.

They should study cells from more people to see how the different versions of virus affect them.

Using these cells, she will see how reducing or increasing the presence of PIAS1 affects many different processes in HD neurons to gain an understanding of how we can use the system to develop new treatments for HD.

Because most bodily cells have cortisol receptors, it affects many different functions in the body.

CONCLUSIONS: Despite affecting different types of inflammatory cells, levothyroxine and selenomethionine exhibit a similar systemic antiinflammatory effect in euthyroid females with Hashimoto's thyroiditis.

It can also kill many different types of cancer cells by triggering apoptosis (programmed cell death) without affecting normal cells.

Key features of the lesson are: The lesson about how altitude, latitude, ocean currents, air masses and air pressure cells affect the climates of different places.

Different types of cancer can affect all parts of a dog's urinary tract, but transitional cell carcinoma (TCC) of the bladder is the most common.

The eyes contain two different types of photoreceptor cells that affect the way everyone sees things, and this is true of both dogs and people.

Analyzed effects of different pH environment, and cell wall affecting agents on the growth of wild and mutant cell lines of Candida albicans.