Sentences with phrase «affects dystrophin»

For example, researchers would like to know how the drug affects dystrophin production in muscles throughout the limbs and whether some muscles may get a bigger boost than others.

Cardiologist Kirk Knowlton of the University of San Diego and his colleagues wanted to find out whether the Coxsackie B virus also affected dystrophin.

Not exact matches

The result was the largest deletion ever observed in the dystrophin gene using CRISPR / Cas9, and the study was the first to create corrected human iPS cells that could directly restore functional muscle tissue affected by Duchenne.

DMD is a rare disease affecting primarily boys and is caused by defects in the gene that makes the dystrophin protein.

Duchenne muscular dystrophy, which strikes in 1 out of 5,000 newborn boys, results from a genetic deficiency in dystrophin, a protein involved in repairing muscle fibers affected by daily movement and activities such as exercise.

If any one exon gets a debilitating mutation, the chain does not get built.Without dystrophin providing support, muscle tends to shred and slowly deteriorate.Duchenne affects one in 5,000 newborn males.