But it wasn't known exactly how either of these changes
affects hair pigment.
Not exact matches
The genes that
affect hair colour also
affect other cancer types, while other
pigment genes
affect the chances of having Crohn's and other forms of bowel disease.
Since merle only visibly
affects the fully
pigmented hair tips, if the dog has minimal dark
hair tips (and those are all or mostly merled), it could easily appear to be a solid colored dog.
This
pigment is produced only in the coat and
affects only
hair color while eumelanin
affects eye and nose color.
Hair loss and
pigment changes in the
affected area are also typical.