Not exact matches
Using rodent models of opiate addiction, Dr. Laviolette's research has shown that opiates
affect pathways of associative
memory formation in multiple ways, both at the level of anatomy (connections between neurons) and at the molecular levels (how molecules inside the brain
affect these connections).
«Based on these findings, it was particularly interesting to find out if and to what extent the mGlu5 receptor
affects synaptic plasticity and, consequently,
memory formation in the CA3 region,» explains Hagena.
The identified miRNAs
affected either neuronal physiology underlying
memory formation or the development of the nervous system.
They found that dexamethasone, a widely prescribed steroid for inflammatory conditions,
affects the expression of fkbp5 in the brain, preventing the
formation of the fearful
memories that are the hallmark of PTSD.
Given these findings, University of Alabama at Birmingham neurobiologist David Sweatt and Johns Hopkins University neurobiologist Hongjun Song wondered if methyl groups
affected long - term
memory formation.
The study came about when, a few years ago, Cho and Kim were selectively labeling and stimulating hippocampal neurons that project to the mPFC, and examining how this manipulation
affects fear
memory formation in mice.
The researchers wanted to see how brain function is
affected by canola oil consumption, so the study was focused on the impairment of
memory and the
formation of neurofibrillary tangles and amyloid plaques in the Alzheimer's mouse model.