Cerebellar and extrapyramidal nuclear abiotrophy —
Affects other brain cells besides the Purkinje cells
«Drugs like morphine hijack the body's natural painkilling mechanisms, such as those used by endorphins, but because they act within the central nervous system, they can
affect other brain cells that use similar pathways, leading to side effects such as addiction or sleepiness,» says Professor Gamper.
Not exact matches
But the enzyme has
other jobs in the
brain, such as potentially
affecting the ability of nerve
cells to communicate properly.
A new study is the first to reveal how sleep deprivation disrupts our
brain cells» ability to communicate with each
other, leading to temporary mental lapses that
affect memory and visual perception.
Neurodegenerative diseases are caused by the death of neurons and
other cells in the
brain, with different diseases
affecting different regions of the
brain.
But this came from work in my laboratory and
others that suggested that nerve
cells in
affected regions of the Alzheimer
brain looked like they were trying to divide.
Researchers from Hiroki Taniguchi's lab at the Max Planck Florida Institute for Neuroscience (MPFI) published a study in eNeuro in May 2017 showing for the first time that a unique type of inhibitory interneuron called chandelier
cells — which are implicated in several diseases
affecting the
brain such as schizophrenia and epilepsy — seem to develop their connections differently than
other types of neurons.
«These results suggest that inflammation in mid-life may be an early contributor to the
brain changes that are associated with Alzheimer's disease and
other forms of dementia,» said study author Keenan Walker, PhD, of Johns Hopkins University School of Medicine in Baltimore, Md. «Because the processes that lead to
brain cell loss begin decades before people start showing any symptoms, it is vital that we figure out how these processes that happen in middle age
affect people many years later.»
However, even though these patients don't have a blood problem, vis a vis these diseases typically
affect brain, heart, and or
other organs, they have to undergo myeloablative chemotherapy so their body doesn't reject the donor
cells.
Health improvement (allowing to post - pone / escape the diseases and thus live, healthier / disease - free longer, but not above human MLSP of around 122 years; thus these therapies do not
affect epigenetic aging whatsoever, they are degenerative aging problems not regular healthy aging problem (except OncoSENS - only when you Already Have Cancer - which cancer increases epigenetic aging, but cancer removal thus does not change anything / makes no difference about what happens in the
other cells / about what happens in the normal epigenetic «aging» course in Normal non-cancerous healthy cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to M
cells / about what happens in the normal epigenetic «aging» course in Normal non-cancerous healthy
cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to M
cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not
affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent
Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to M
Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent
cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to M
cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general
brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the
brain is causal to how long we live; keeping
brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer
brain function means longer heavy
brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger
brain for their age), and both are correlated to MLSP).
How the
other great apes lost the
cells remains unknown, but the researchers theorize genetic disruptions
affecting the
cells» migration to different parts of the
brain, differentiation, or survival could have led to the loss.
«And eventually, you do it long enough and it starts impacting
other systems... immune responses; it can
affect the heart; it
affects brain cells.
(In reality, they
affect many
other systems of the body, including the
brain, the immune system, inflammatory cytokines, and perhaps most importantly, the mitochondria (the energy generators in our
cells)-RRB-.