Sentences with phrase «affects signaling in the brain»

«We hope that in the future, by fully understanding how this gene affects signaling in the brain, we may be able to identify drugs to restore the normal signaling balance in neurons and improve cognitive and social function in patients,» says lead author Dr. M. Chiara Manzini.

Not exact matches

Compared to the brains of people without bipolar disorder, the researchers found that the MRI signal was elevated in the cerebral white matter and the cerebellar region of patients affected by bipolar disorder.

For example, being hungry affects the body, and signals associated with metabolism, as well as signals in the brain.

Hence, the researchers considered it worthwhile to investigate how alterations in BDNF signalling affect memory functions and brain pathology.

This suggests that interferon gamma normally dampens brain signals in this region — and that it affects social behavior.

The team demonstrated that GPR158 affects key signaling pathways involved in mood regulation in the region of the brain called prefrontal cortex, though the researchers emphasized that the exact mechanisms remain to be established.

Plunges in energy use could signal decline in brain function, and the researchers decided to focus on the hippocampus, a part of the brain known to be affected in Alzheimer's.

Poon believes this discovery will spawn a new generation of programmable microimplants — sensors to monitor vital functions deep inside the body; electrostimulators to change neural signals in the brain; and drug delivery systems to apply medicines directly to affected areas.

Parkinson's disease is caused by loss of the brain signaling chemical dopamine and affects about 1 million people in the United States.

ALS is a progressive neurodegenerative disease that affects neuronal cells in the brain and the spinal cord, which send signals to control muscles throughout the body.

It has demonstrated that physical changes in myelin itself - the coating of the auditory nerve carrying sound signals to the brain — affect our ability to hear.

Myelin disorders can affect nerve signal transmission in the brain and spinal cord, leading to cognitive, motor and sensory problems.

The researchers said that pesticides could impair brain development and signaling in a way that affects social interactions, learning and behavior.

«For many years, the focus has been on finding drugs that block channels and receptors in the brain that affect the way signals are made between cells.

In the course of this work, he has pioneered several new approaches in the fruit fly that have had important implications for mammalian neurobiology, including: the demonstration that the fruit fly has a sleep - like behavior similar to that of mammals, studies of physiological and behavioral consequences of mutations in a neurotransmitter system affecting one of the brain's principal chemical signals, studies making highly localized genetic alterations in the nervous system to alter behavior, and molecular identification of genes causing naturally occurring variation in behavioIn the course of this work, he has pioneered several new approaches in the fruit fly that have had important implications for mammalian neurobiology, including: the demonstration that the fruit fly has a sleep - like behavior similar to that of mammals, studies of physiological and behavioral consequences of mutations in a neurotransmitter system affecting one of the brain's principal chemical signals, studies making highly localized genetic alterations in the nervous system to alter behavior, and molecular identification of genes causing naturally occurring variation in behavioin the fruit fly that have had important implications for mammalian neurobiology, including: the demonstration that the fruit fly has a sleep - like behavior similar to that of mammals, studies of physiological and behavioral consequences of mutations in a neurotransmitter system affecting one of the brain's principal chemical signals, studies making highly localized genetic alterations in the nervous system to alter behavior, and molecular identification of genes causing naturally occurring variation in behavioin a neurotransmitter system affecting one of the brain's principal chemical signals, studies making highly localized genetic alterations in the nervous system to alter behavior, and molecular identification of genes causing naturally occurring variation in behavioin the nervous system to alter behavior, and molecular identification of genes causing naturally occurring variation in behavioin behavior.

NF - KappaB affects many biological processes, but its role in signaling in the brain is not well understood.

In the Lu laboratory, we aim to elucidate the signaling cascades that establish neural circuit connections during brain development, to understand how sensory experiences and environmental factors affect neural circuit wiring and cognitive behaviors, and to identify novel factors required to maintain the health of neural circuits during aging.

Researchers have found a new group of cells in the retina that directly affect the biological clock by sending signals to a region of the brain which regulates our daily (circadian) rhythms.

How exactly the drug works is not understood, although it's believed that it calms down hyperactive neurons and could affect the release of neurotransmitters, which are chemicals in the brain that transmit signals from one neuron to another.

Throw in your immune system's response (about 70 percent of your immune system lies in your gut), which includes the secretion of all sorts of inflammatory signals that also affect your brain, and you become chronically inflamed, leading to depression, erratic behavior, and even memory problems.

So, we see some clues here that there are things going on that are perhaps affecting the brain's signaling to the adrenal glands, or to the testes on this first custom panel in which we tested ACTH, luteinizing hormone, like you just mentioned along with some of these other variables that are on this panel.

Functions of Testosterone in Your Body In its role as an androgen hormone, testosterone contributes its signals to a variety of areas that can affect bone and muscular strength, brain functions, libido, and even emotional well - beinin Your Body In its role as an androgen hormone, testosterone contributes its signals to a variety of areas that can affect bone and muscular strength, brain functions, libido, and even emotional well - beinIn its role as an androgen hormone, testosterone contributes its signals to a variety of areas that can affect bone and muscular strength, brain functions, libido, and even emotional well - being.

In its role as an androgen hormone, testosterone contributes its signals to a variety of areas that can affect bone and muscular strength, brain functions, libido, and even emotional well - being.

But in less than a minute, it creates positive changes in your heart rhythms, which then sends powerful signals to the brain that directly affect your body via the mind - body connection.

Aβ is believed to penetrate neuronal plasma membranes, where it leads to lipid peroxidation.10 It has also been implicated in deactivating a subunit of the pyruvate dehydrogenase complex, thereby inhibiting conversion of pyruvate to acetyl CoA and the eventual production of cellular energy as ATP.32 Another way Aβ affects glucose metabolism in the brain is that fragments of Aβ disrupt insulin signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant at synapses, so if the integrity of the synapse itself has been compromised, the receptors won't function effectively.

This affects dopamine tolerance (note: dopamine is a neurotransmitter, one of those chemicals that is responsible for transmitting signals in between the neurons of the brain) and makes you feel like you have to eat more.

These results indicate that propionate suppressed food intake by affecting reward - driven eating behavior, although the researchers didn't find any significant association between changes in brain signals and food intake.

What it does in the body: HCG signals the hypothalamus (area of the brain that affects metabolism) to mobilize fat stores.

As the tooth weakens, bacteria and inflammation spread, the nerve can be affected, sending impulses to the brain signaling that there is something wrong — in the form of pain.