Sentences with phrase «affects synapse»

Mutations in this receptor are known to affect synapse connectivity and cause abnormal social behavior in mice.

«Up - regulating MHCI is essential for the maternal immune response, but changing MHCI activity in the fetal brain when synaptic connections are being formed could potentially affect synapse density,» Boulanger said.

Astrocytes can regulate neuronal synapses by secreting factors that affect both synapse formation and synaptic function.

Not exact matches

The lipid type, ceramide, also has a functional role in various signaling pathways and affects synaptic function, although its primary role is not in the synapse, but providing structure in cell membranes.

Ben Barres, a professor of neurobiology, developmental biology and neurology at the Stanford University School of Medicine, said that while it is known that both insulin - receptor signaling increases synapse density, and MHCI signaling decreases it, the researchers are the first to show that MHCI actually affects insulin receptors to control synapse density.

To address this question, the researchers made use of mice with mutations that affect different aspects of synapse unsilencing.

The type of neurotransmitter and the strength of each connection to the synapse affect the functioning of the recipient neuron.

The mutation, which has been found in people with ADHD, autism and bipolar disorder, affects the function of DAT, a protein that regulates the brain's supply of the neurotransmitter by removing excess dopamine from the synapse, or the space between nerve cells.

The study does not explain what does maintain working memories if low - level activation doesn't, but changes in synaptic weights — or the potential one neuron has to affect the behavior of another across a synapse — might be the answer.

Aβ is believed to penetrate neuronal plasma membranes, where it leads to lipid peroxidation.10 It has also been implicated in deactivating a subunit of the pyruvate dehydrogenase complex, thereby inhibiting conversion of pyruvate to acetyl CoA and the eventual production of cellular energy as ATP.32 Another way Aβ affects glucose metabolism in the brain is that fragments of Aβ disrupt insulin signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant at synapses, so if the integrity of the synapse itself has been compromised, the receptors won't function effectively.

The H reflex is regarded as a measure of α - motor neuron excitability at the spinal level, but it can also be affected by inhibitory effects from Golgi tendon organ Ib afferents or by factors affecting neurotransmitter release at the Ia / α - motor neuron synapse (Palmieri et al. 2004).

Synapse conducted modeling of the California ISO (CAISO) area using PLEXOS to assess loads and emissions throughout California based on various California Public Utilities Commission scenarios in connection with the Long Term Procurement Plan proceeding affecting the three largest investor - owned utilities in California.

It won't affect those who only use their mouse on one computer, but those who game or work on various computers may find having to re-download and install Synapse multiple times to be a bit of a hassle.