Sentences with phrase «after altering a gene»

Rassoulzadegan stumbled upon her rodent scofflaws after altering a gene in gray mice so that their feet and the tips of their tails turned white.

Not exact matches

Where is the clear line in a progression from (1) using animal insulin to treat diabetes, to (2) using gene remodeling techniques to grow insulin in a host bacterium that will reproduce rapidly and from which a plentiful supply of insulin can be harvested, to (3) genetic surgery to replace the defective gene in a person diagnosed as diabetic, to (4) genetic surgery immediately after fertilization in order to replace the defective gene and alter the germ cells which would otherwise have transmitted the disease to one's offspring?

Nearly five years after the gene - editing tool debuted, researchers for the first time have used it to alter genes in viable human embryos.

And their genes are easier to manipulate than those of their mammalian counterparts — by altering Sod1, Wu created flies that died after only about two weeks, a quarter of their normal life span.

This gene gives instructions for an enzyme that attaches the appendage to the glucose chain after it's produced, altering the cellulose just before it leaves the cell.

After bombarding hundreds of Caenorhabditis elegans worms with DNA - altering chemicals and screening the results, he found that the deletion of just one gene rendered the worms almost completely resistant to alcohol.

Years of diabetes research carried out on mice whose DNA had been altered with a human growth hormone gene is now ripe for reinterpretation after a new study by researchers at KU Leuven confirms that the gene had an unintended effect on the mice's insulin production, a key variable in diabetes research.

After exploiting a technology that allowed them to activate each of nearly 16,000 genes individually in human melanoma cell lines containing mutant BRAF, the authors then treated the panel of cells with the drugs and monitored which cells showed altered drug sensitivity.

For the past 3 months, faculty and staff members at the University of Pennsylvania's Institute for Human Gene Therapy have been trying to understand why a relatively fit 18 - year - old with an inherited enzyme deficiency died on 17 September, 4 days after doctors at Penn injected a genetically altered virus into his liver.

Güler and Wheeler call their synthetic gene «Magneto,» after a Marvel Comics cartoon character who can alter magnetic fields.

However, within the group that remain altered after 24 h are some genes that may underly the positive effects of hypoxic preconditioning [43,63].

GSEA analysis revealed that these genes were not affected by either hypoxia or altered after recovery.

Hulmi et al. [87] found that 21 weeks of supplementing 15 g of whey before and after resistance training increased size and altered gene expression favorably towards muscle anabolism in the vastus lateralis.