Sentences with phrase «after cocaine exposure»

Next, the researchers gave the flies a single dose of cocaine then monitored the activity of tyrosine decarboxylase (TDC), an enzyme that normally shows a spike in activity after cocaine exposure.

Not exact matches

A prospective cohort study found the SIDS rate to be significantly increased for infants exposed in utero to methadone (OR: 3.6 [95 % CI: 2.5 — 5.1]-RRB-, heroin (OR: 2.3 [95 % CI: 1.3 — 4.0]-RRB-, methadone and heroin (OR: 3.2 [95 % CI: 1.2 — 8.6]-RRB-, and cocaine (OR: 1.6 [95 % CI: 1.2 — 2.2]-RRB-, even after controlling for race / ethnicity, maternal age, parity, birth weight, year of birth, and maternal smoking.229 In addition, a meta - analysis of studies that investigated an association between in utero cocaine exposure and SIDS found an increased risk of SIDS to be associated with prenatal exposure to cocaine and illicit drugs in general.230

In these images of rat brains, differences in gene expression of genes for fibroblast growth factor 2 (FGF2, top set) and dopamine 2 receptor (D2, bottom sett) can be seen in rats of two breeds before (left) and after (right) cocaine exposure.

«These experiments with cell type - specific pharmacology provide direct evidence for the necessity of NMDA - Rs in dopamine neurons for the synaptic plasticity observed 3 - 5 hours after exposure to cocaine in vitro, leaving open the molecular explanation for the potentiation AMPA - Rs that occurs after many days of NMDA - R inactivity in dopamine neurons in vivo.

There was some evidence for an effect of exposure status (i.e., maternal cocaine or opiate use during pregnancy) on parenting stress, although this effect was not significant after controlling for maternal psychopathology (BSI scores).