New Insights on Pain and Opioid Use in People With Sickle Cell Disease
After Hematopoietic Stem Cell Transplant (March 12, 2018)
University of Texas M.D. Anderson Cancer Center Tumor - specific alloantigen - anergic donor - derived T - cell therapy
after hematopoietic stem - cell transplantation
Studies to improve the knowledge of genetic diseases include the natural history study for MLD, advanced diagnosis and natural history of primary immunodeficiencies and immunedysregulatory disorder, and immune reconstitution
after hematopoietic stem cell transplantation for genetic disorders.
Accelerated aging of immune system
after hematopoietic stem cell transplantation Researchers demonstrated that hematopoietic stem cell transplantation in patients with hematological malignancies significantly accelerates aging of immune system.
«Immunotherapy drug nearly eliminates severe acute graft - versus - host disease: Drug used to treat rheumatoid arthritis improves survival
after hematopoietic stem cell transplant.»
Not exact matches
Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a
hematopoietic stem cell transplant (HSCT)
after pre-treatment with immunosuppressive drugs only.
While some previous studies found that maintenance lenalidomide
after autologous
hematopoietic stem cell transplant improved overall survival for newly diagnosed multiple myeloma patients, others showed no benefit to this approach.
Last month she filed a request with the U.S. Food and Drug Administration to offer
hematopoietic stem cells to fetuses with α thalassemia, a severe form of the disease that is fatal before or soon
after birth.
The findings, published today in Nature, demonstrate that these myeloproliferative neoplasias only appear
after damage to the microenvironment that sustains and controls the
hematopoietic stem cells — the cells that produce the cells of the blood and the immune system.
Beilhack and colleagues found that a slightly modified version of STAR2 has a similar effect on human T reg cells, suggesting that the approach could also prevent GvHD in leukemia and lymphoma patients
after bone marrow or
hematopoietic stem cell transplants.
Nearly 30 years
after the discovery of the
hematopoietic stem cell, Stanford researchers have found a marker that allows them to study the version of these stem cells that continues to replicate.
A Phase 3 Open - Label Randomized Study of Quizartinib (AC220) Monotherapy Versus Salvage Chemotherapy in Subjects with FLT3 - ITD Positive Acute Myeloid Leukemia (AML) Refractory To or Relapsed
After First - line Treatment With or Without
Hematopoietic Stem Cell Transplantation (HSCT) Consolidation
• Subject is refractory to or relapsed
after first - line AML therapy (with or without
hematopoietic stem cell transplant (HSCT)-RRB-.
Along the way, we became interested in using cord blood as an alternative donor source for
hematopoietic reconstitution
after myeloablative therapy.
Hematopoietic stem cells express the markers CD34 and CD133 and can repopulate a myeloablated recipient
after allogeneic or autologous transplantation.
Functional rescue of dopaminergic neuron loss in Parkinson's disease mice
after transplantation of
hematopoietic stem and progenitor cells, EBioMedicine, in press.
By transplanting Wnt - activated
hematopoietic stem and progenitor cells (HSPCs) we demonstrated that Muller cells can be reprogrammed in vivo
after fusion with HSPCs.
However,
after transfecting ES cells with the
hematopoietic transcription factor HOXB4, cells can expand stably in vitro and in vivo [9]--[11].
Here, ES cells transduced with HOXB4 were analyzed for the expression of
hematopoietic markers
after 26 days of differentiation.
Functional rescue of dopaminergic neuron loss in Parkinson's disease mice
after transplantation of
hematopoietic stem and progenitor cells.