One study showed that in the first year
after menarche (start of menstruation), 80 % of girls did not ovulate, meaning they did not make progesterone.
Originated 1970s by Dr. Henry Lemon, who tested estrogen levels in 24 hour urine samples and found that an EQ > 1 strongly correlated with a higher survival rate after breast cancer.24 Further research conducted by Lemon, Heidel, et al., a meta - analysis of published fractional estrogen excretion collected from 2,846 healthy women worldwide aged 15 to 59 years, with a risk of breast cancer varying five-fold, found that an EQ < 1 reflects increased rates of oxidation of estrone or estradiol to 4 - OH catechols (also referred to in the literature as the 3,4 - catechol estrogen quinones), which have been identified as the principal proximal human mammary carcinogens
after menarche, while an EQ > 1 reflects conversion to protective 2 - OH estrogen metabolites.2526
Not exact matches
For most girls, their first menstrual period, or
menarche (say: MEH - nar - kee), begins about 2 to 2 1/2 years
after breast development starts.
Early
menarche remained linked to higher risks of coronary heart disease and deaths from cardiovascular disease and cancer
after the researchers accounted for a number of other factors — such as age, BMI, smoking, exercise habits and education.