Liang Xu, Ph.D. member of the KU Cancer Center's Drug Discovery, Delivery and Experimental Therapeutics program and associate professor of molecular biosciences at KU, has discovered that targeting a cell - surface receptor called «CD44s» can block pancreatic tumor formation and recurrence
after radiotherapy.
While gold nanospheres, without any accompanying drug, were found to cause significant cell damage, treatment - resistant cell populations did eventually recover several days
after the radiotherapy.
Not exact matches
The targeted
radiotherapy shrank tumors for 71 % of patients who had already failed standard chemotherapy, but these results came from a small trial that started with 30 patients and then added another 20
after positive data started rolling in.
Model of tumor growth in a rat brain before radiation treatment (left) and
after one session of
radiotherapy (right).
Approximately one year
after successful treatment with cytotoxic chemotherapy and
radiotherapy, patients with advanced Small Cell Lung Cancer (SCLC), which primarily affects heavy smokers, generally relapse with recurrence of tumours that are resistant to further chemotherapy.
Breast cancer patients who have
radiotherapy targeted at the original tumour site experience fewer side effects five years
after treatment than those who have whole breast
radiotherapy, and their cancer is just as unlikely to return, according to trial results published in The Lancet.
«Invisible tattoos» could improve body confidence
after breast cancer
radiotherapy.»
Steven Landeg, a senior radiographer from the Royal Marsden, who is presenting the data, said: «These findings suggest that offering fluorescent
radiotherapy tattoos as an alternative to dark ink ones could help ameliorate the negative feelings some women feel towards their bodies
after treatment.
«Prostate cancer patients who receive permanent
radiotherapy implants twice as likely to be free of cancer
after five years.»
«We have identified a subgroup of older patients at sufficiently low risk of recurrence for whom omission of postoperative
radiotherapy after breast - conserving surgery and adjuvant endocrine therapy is a reasonable option.
However, what our trial has shown is that although this is still the case, the proportion of women who will actually have a recurrence without
radiotherapy is very small (less than 5 percent), five years
after treatment,» said Ian Kunkler, F.R.C.R., professor of clinical oncology at the Edinburgh Cancer Research Center in the University of Edinburgh.
Omission of
radiotherapy is a reasonable option for women age 65 or older who receive hormone therapy
after breast - conserving surgery for hormone receptor - positive, axillary node - negative breast cancer, according to results of the PRIME 2 trial presented at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10 - 14.
Cancer stem cells, a type of self - renewing cell found in tumors, are of particular interest because they are the main cell type responsible for tumor progression and for resistance to chemotherapy and
radiotherapy, and therefore a major cause of tumor recurrence
after treatment.
After his first diagnosis, he had been told the chances of relapse were small and had therefore opted to forego
radiotherapy, fearing the secondary effects of the treatment; he eventually regretted that decision.
At Colchester General Hospital, the researchers looked at MR scans taken both before treatment and six weeks
after the patients had completed chemotherapy and
radiotherapy, and found that the patients whose tumors were less heterogeneous — ie more uniform — in terms of texture parameters six weeks
after treatment were more likely to survive longer.
Appearing in Lancet Oncology, long term results of EORTC trial 22921 with 10.4 years median follow - up show that 5 - FU (fluorouracil) based adjuvant chemotherapy
after preoperative (chemo)-
radiotherapy for patients with cT3 - resectable T4 M0 rectal cancer does not improve survival or disease - free survival.
Whole brain
radiotherapy (WBRT) significantly improves tumor control in the brain
after SRS, yet because of its association with cognitive decline, its role in the treatment of patients with brain metastases remains controversial.
After the neo-adjuvant chemotherapy, the patients were then given accelerated
radiotherapy.
Radiotherapy to the chest wall and regional lymph nodes (under the arm, above the collar bone and under the breast bone), known as regional nodal irradiation, is used
after mastectomy in women with node - positive breast cancer who are treated with adjuvant systemic therapy.
The team at Barts Cancer Institute, part of Queen Mary University of London, have found that a molecule, called focal adhesion kinase (FAK), signals the body to repair itself
after chemotherapy or
radiotherapy, which kill cancer cells by damaging DNA.
Treating patients with high - dose
radiotherapy after chemotherapy and surgery for malignant pleural mesothelioma does not achieve improvements in local relapse and overall survival, according to data from a prospective randomized phase II trial presented at ESMO 2014 Congress in Madrid.
«Mesothelioma remains a difficult disease to find better treatment options for, so we asked whether high - dose hemithoracic
radiotherapy would decrease the rate or delay the time of local recurrence
after chemotherapy and radical surgery,» says lead author Prof Rolf A. Stahel, from the Clinic and Policlinic for Oncology, at the University Hospital Zurich, Switzerland, and current President of the European Society for Medical Oncology.
The researchers evaluated blood and renal dosimetry
after the first and second courses of
radiotherapy to discern the best possible dose of Y - 90 DOTATOC for successive courses.
In the second case, the reconstruction was achieved as planned, but only
after a three - month delay and required anticoagulation therapy and pre-operative
radiotherapy.
At Colchester General Hospital, the researchers looked at MR scans taken both before treatment and six weeks
after the patients had completed chemotherapy and
radiotherapy, and found that the patients whose tumours were less heterogeneous — ie more uniform - in terms of texture parameters six weeks
after treatment were more likely to survive longer.
Adjuvant lymph - node field
radiotherapy versus observation only in patients with melanoma at high risk of further lymph - node field relapse
after lymphadenectomy (ANZMTG 01.02 / TROG 02.01): 6 - year follow - up of a phase 3, randomised controlled trial.
Inclusion Criteria: • Diagnosed with Stage II / III carcinoma of the esophagus or gastroesophageal junction • Completed pre-operative chemo
radiotherapy followed by surgery • Diagnosed with residual pathologic disease
after being surgically rendered free of disease with negative margins following complete resection Exclusion Criteria: • Diagnosed with cervical esophageal carcinoma • Diagnosed with Stage IV resectable disease • Did not receive concurrent chemoradiotherapy prior to surgery
Olaparib is a PARP inhibitor, which is already used to treat certain ovarian cancer patients and prevents damaged cancer cells from repairing themselves
after chemotherapy or
radiotherapy.
Radiation Therapy Prolongs Life in Men with Recurrent Prostate Cancer Men whose tumors recur
after prostate cancer surgery are three times more likely to survive their disease long term if they undergo
radiotherapy within two years of the recurrence.
And so one month
after completing
radiotherapy, I started studying nutritional therapy.
After a year of treatment, which involved a partial mastectomy to remove a malignant tumor, followed by eight months of
radiotherapy and chemotherapy, the pop star was given the all clear in November 2006.