Sentences with phrase «after spinal cord injury in»

Here Dr. Reimer and his team asked the question, «what happens to mature oligodendrocytes after a spinal cord injury in adult zebrafish?».

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Physical therapy aimed at rebuilding neural pathways can often improve a patient's level of functioning in the months and years after a spinal cord injury.
The 1948 British Olympics was the first year to see disabled athletes participating after the German refugee, Ludwig Guttmann, hosted a competition at Stoke Mandeville Hospital where he was in charge of Second World War patients with spinal cord injuries.
The Regenerative Research Foundation in Rensselaer, an affiliate of the Neural Stem Cell Institute, will receive nearly one - fifth of the funds, or almost $ 1.1 million, for work aimed at promoting spinal cord regeneration after injury.
Albert Einstein College of Medicine in the Bronx received the largest grant, of nearly $ 1.2 million, for research intended to improve urological function after spinal cord injury.
Here, mice that lack protein kinase C gamma (PKCγ) displayed normal responses to acute pain stimuli, but they almost completely failed to develop a neuropathic pain syndrome after partial sciatic nerve section, and the neurochemical changes that occurred in the spinal cord after nerve injury were blunted.
Short - term peripheral nerve stimulation may be a new approach to preventing long - term changes in nerve and muscle function and improving rehabilitation outcomes after spinal cord injuries.
«Many of the current Phase I trials for spinal cord injury are run in the acute phase, which is right after injury.
Eight people who have spent years paralyzed from spinal cord injuries have regained partial sensation and muscle control in their lower limbs after training with brain - controlled robotics, according to a study published Aug. 11 in Scientific Reports.
A team of researchers led by the University of South Carolina's Jeff Twiss just reported an innate repair mechanism in central nervous system axons that might be harnessed to regenerate nerves after brain or spinal cord injuries.
«Nanoparticles limit damage in spinal cord injury: Injection after an injury reduces inflammation and scarring.»
Together, studies in zebrafish and mammalian models could inform new ways to manipulate glial cells after human spinal cord injury
New research in mice indicates that a drug commonly used to suppress the immune system in recipients of organ transplants may also reduce tissue damage and neuropathic pain after spinal cord injury.
Rapamycin treatment four hours after spinal cord injury significantly improved locomotor function and reduced mechanical and thermal hypersensitivity in the hindpaws.
«Technique to promote nerve regeneration after spinal cord injury restores bladder function in rats.»
Published in Nature Medicine on May 1, 2017, the study demonstrates chronic ischemic hypoxia (lack of blood and oxygen) after spinal cord injury and how blood flow plays a key role in the cause and treatment of motor disorders.
Neuroscientists found that spinal blood flow in rats was unexpectedly compromised long after a spinal cord injury (chronically ischemia), and that improving blood flow or simply inhaling more oxygen produces lasting improvements in cord oxygenation and motor functions, such as walking.
He also showed in 2012 that paralyzed rats could recover after spinal cord injury after a few weeks of rehabilitation, combining electro - chemical stimulation and physiotherapy that uses a robotic harness.
Partially paralyzed rodents walk almost normally after human embryonic or fetal brain stem cells repaired their spinal cord injuries in recent studies.
After other researchers reported that bone marrow stem cell therapy led to a modest but promising 5 percent improvement in the regeneration of sensory nerve fibers in rats with spinal cord injuries, he performed a critical reality check.
The study introduced here focused on a population of support cells in the spinal cord that helps to protect surviving nerve cells (neurons) after injury: oligodendrocytes and their precursor cells.
Oligodendrocyte death, occurring after a spinal cord injury, activates a process called de-myelination that results first in damage to surviving neuronal connections and finally in death of the affected neurons.
Some examples of the scholars» projects are: effects of estrogen on cardiac fibrosis after myocardial infarction, depression and the growth - hormone axis, substance abuse, stress and nicotine, cardiovascular risk in spinal cord injury, and pharmacogenomics and the treatment of breast cancer in elderly women.
In the years after the visit, his foundation granted about $ 4 million to Edgerton's lab to find a way to train human patients with complete spinal cord injuries to walk again.
«Given the effectiveness of inosine in promoting cortical plasticity, axonal sprouting, and dendritic branching, the present evidence of efficacy after cortical injury in a non-human primate, combined with a long history of safe use, indicates a need for clinical trials with inosine after cortical injury and spinal cord injury,» noted Dr. Moore.
When scientists gave mice an oral drug called LM11A - 31 (designed to prevent neural degeneration in Alzheimer's patients) just hours after a complete spinal cord injury, it limited the death of cells that protect nerve fibers, allowing test rodents to retain their ability to walk and swim.
A new study in mice published in The Journal of Neuroscience details a potential therapeutic strategy that uses stem cells to promote recovery of motor activity after spinal cord injury.
Stylized representation of a newly - discovered signaling pathway active after spinal cord injury, which sees the injured central nervous system use adrenal hormone production to potentially disrupt the immune system in a way that lead to severe infections.
After eight years of work, we were able to identify an entirely new mechanism for how spinal cord injury weakens the immune system,» said principal investigator Dr. Jan M. Schwab, neurologist and physician at Ohio State's Neurological Institute, who collaborated with researchers from several institutes in Germany, along with the University of Alabama in Birmingham, Harvard Medical School and Boston's Children's Hospital.
Pneumonia is the main cause of death in patients both after acute and chronic spinal cord injury.
Neuroscientists have long believed that scar tissue formed by glial cells — the cells that surround neurons in the central nervous system — impedes damaged nerve cells from regrowing after a brain or spinal cord injury.
Here, the research team led by Associate Professor Yukio Nishimura, National Institute for Physiological Sciences (NIPS), Natural Institutes of Natural Sciences (NINS), and Masahiro Sawada, a former graduate student of Kyoto University, and Dr. Hirotaka Onoe, a team leader at RIKEN Center for Life Science Technologies found that the nucleus accumbens, that control motivation in the brain, activates the activity of the motor cortex of the brain, and then promotes recovery of motor function during the early stage of recovery after spinal cord injury.
Dr. Nishimura said, «Our result suggests that in the early stage after brain injury including spinal cord injury, it is important to motivate the patients for promoting functional recovery in rehabilitation.
In the intact monkey, and also in the fully recovered stage (3 months after spinal cord injury), such deficit in hand movement by blocking the activity of the nucleus accumbens was not observeIn the intact monkey, and also in the fully recovered stage (3 months after spinal cord injury), such deficit in hand movement by blocking the activity of the nucleus accumbens was not observein the fully recovered stage (3 months after spinal cord injury), such deficit in hand movement by blocking the activity of the nucleus accumbens was not observein hand movement by blocking the activity of the nucleus accumbens was not observed.
He and colleagues reveal that eight Brazilians paralyzed because of spinal cord injuries regained some small but significant sensation and muscle control in their lower limbs after many months of training with the robotic exoskeleton, and by a virtual reality avatar also controlled by brain signals.
Second - order spinal cord pathway contributes to cortical responses after long recoveries from dorsal column injury in squirrel monkeys
Treatment with the neurosteroid dehydroepiandrosterone promotes recovery of motor behavior after moderate contusive spinal cord injury in the mouse.
NEWARK, Calif., May 31, 2016 (GLOBE NEWSWIRE)-- StemCells, Inc. (NASDAQ: STEM)(the «Company») today announced its decision to terminate the Company's Phase II Pathway Study in spinal cord injury following an in - depth review of data from the study and after obtaining the concurrence of the study's Interim Analysis Data Monitoring Committee (the «IA - DMC»).
After all, nanomaterials currently represent our best hope for developing innovative strategies in the treatment of spinal cord injuries».
The signaling molecule CD95L, known as «death messenger,» causes an inflammatory process in injured tissue after spinal cord injuries and prevents its healing.
The discovery of motor pattern generators, the neural network's underlying movements, in the spinal cord is already being used to re-establish locomotion in people paralyzed after spinal cord injury
Reported MRI data from the SCiStar study that indicates AST - OPC1 cells have durably engrafted in patients post-implantation, demonstrating the potential for AST - OPC1 to prevent lesion cavity formation and possibly reducing spinal cord tissue deterioration after spinal cord injury.
For example, we are using electrical spinal stimulation synchronized with residual muscle activity or movement in order to produce lasting improvements in hand and arm function after spinal cord injury.
«Humans have very limited capacity for regeneration, while other species like salamanders have the remarkable ability to functionally regenerate limbs, heart tissue and even the spinal cord after injury,» said lead researcher Karen Echeverri, PhD, assistant professor in the department of genetics, cell biology and development at the University of Minnesota.
WEST ORANGE, N.J. — August 11, 2015 — The New Jersey Commission on Spinal Cord Research awarded $ 198,000 over two years to Zhiguo (Tony) Jiang, Ph.D., research scientist at Kessler Foundation, to examine the efficacy of using diffusion tensor imaging (DTI) in assessing recovery after spinal cord injury Spinal Cord Research awarded $ 198,000 over two years to Zhiguo (Tony) Jiang, Ph.D., research scientist at Kessler Foundation, to examine the efficacy of using diffusion tensor imaging (DTI) in assessing recovery after spinal cord injury (SCord Research awarded $ 198,000 over two years to Zhiguo (Tony) Jiang, Ph.D., research scientist at Kessler Foundation, to examine the efficacy of using diffusion tensor imaging (DTI) in assessing recovery after spinal cord injury spinal cord injury (Scord injury (SCI).
In September of last year, DARPA reported the case of a 28 year - old man who had been paralyzed for a decade, after suffering a spinal cord injury.
We're using a neural device to make long - term changes in neural circuits after spinal cord injury.
Matt's Testimonial After a spinal cord injury left Matt with major disabilities, Matt describes how a change in attitude allowed him to conceive of a life fully healed.
Many people are also involved in an auto accident or other trauma that can often sustain a brain or spinal cord injury — sometimes so apparently minor that many doctors or hospitals say you're fine, even after an MRI or CT scan.
Furthermore, alternate - day fasting leads to increased functional recovery after experimentally induced spinal cord injuries in rats, independently if the alternate - day fasting regimen is implemented prior or after the spinal cord is injured (27,50).
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