«Our study has provided basic evidence that curcumin protects
against Mycobacterium tuberculosis infection in human cells,» said Dr. Xiyuan Bai, lead author of the study.
Steven A. Porcelli, M.D. Albert Einstein College of Medicine Defining the protective human CD8 + T - cell response
against Mycobacterium tuberculosis
Research Focus: My research projects are focused on defining the T cell responses
against Mycobacterium tuberculosis, the causative agent of tuberculosis disease.
Two of these enzymes are already being studies as potential drug targets; one
against Mycobacterium tuberculosis and another against another type of worm.
These cells quench the function of T - cells and other immune cells, which participate in the immune response
against the mycobacteria.
Gladiolin is structurally related to etnangien, a highly unstable antibiotic from Sorangium cellulosum that is also active
against Mycobacteria.
Not exact matches
Researchers at China's Northwest Agriculture and Forestry University devised a CRISPR / Cas 9 technique to give cloned dairy cows a leg up
against the bacteria behind bovine tuberculosis (
Mycobacterium bovis).
The study, «The efficacy of the BCG vaccine
against newly emerging clinical strains of
Mycobacterium tuberculosis,» was published in the journal PLOS One in September.
To learn how
Mycobacterium tuberculosis mounts a defense
against a drug, Baliga is first looking within the bacterium, identifying the genes, proteins and other molecules that interact as the microbe infects a host.
The study, «The efficacy of the BCG vaccine
against newly emerging clinical strains of
Mycobacterium tuberculosis,» was published in September.
She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response
against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to
Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.
Her research involves preclinical immunology and efficacy of vaccines
against H5N1 pandemic influenza, malaria, and
Mycobacterium tuberculosis using mouse, ferret and guinea pig models.
The aim of this project is to fight
against Multi-Drug Resistant (MDR)
Mycobacterium tuberculosis (M. tuberculosis)(TB) and Methicillin Resistant Staphylococcus aureus (MRSA), leading to serious diseases which usually require intensive care treatment with a long hospitalization.
Lindestam Arlehamn CS, Gerasimova A, Mele F, Henderson R, Swann J, Greenbaum JA, Kim Y, Sidney J, James EA, Taplitz R, McKinney DM, Kwok WW, Grey H, Sallusto F, Peters B, Sette A. Memory T cells in latent
Mycobacterium tuberculosis infection are directed
against three antigenic islands and largely contained in a CXCR3 + CCR6 + Th1 subset.
, Evaluation of the Antimicrobial Properties of the Essential Oil of Myrtus communis L.
against Clinical Strains of
Mycobacterium spp., 2010
In general, this class of drug is not effective
against Staphylococcus, Streptococcus, Brucella, Mycoplasma,
Mycobacteria, or anaerobic bacteria.
These natural antimicrobial peptides (AMPs) are active
against small and large bugs alike, even pathogens such as tuberculosis,
Mycobacterium tuberculosis, and the dastardly Staphylococcus aureus.