Sentences with phrase «against a specific disease target»
To make a compound work better against a specific disease target, medicinal chemists optimize the drug, tweaking its structure or physical properties to make it more effective and safer.
http://www.sciencemag.org/
The new process, called Extensive Combinatorial Refinement (ExCoR), could help improve the development of drug candidates that depend to a great degree on detailed structural analysis to determine how they work against specific disease targets.
Not exact matches
The Cancer Gene Census (CGC) database contains 547 such gene across various cancer types.5 Remarkably, few driver genes having specific point mutations appear to be sufficient to rewire signalling networks in cancer, 1 which at the same time shows that — at least from the mutational side — cancer does not consist of an «infinite» number of different diseases, and in many cases treatment options targeted against driver genes might be transferred from one case to the next.