Antiviral flu medications like Tamiflu, Relenza and Rapivab also remain quite effective
against all circulating strains of flu.
We found that the mutations in two amino acids out of more than 300 in one key region of the hemagglutinin protein were enough to lower efficacy to 19 percent
against all circulating strains.»
Not exact matches
A part of the research will include analyzing exactly why this year's flu vaccine proved so ineffective
against the most common
strains circulating (the shot was just 25 % effective
against influenza A
strains).
These included the past two flu seasons in which vaccines offered only limited protection
against the most widely
circulating strain of influenza A.
Both drift and shift make these proteins unrecognizable to the antibodies present in people that were previously inoculated
against the flu virus, which now
circulates as more than 90
strains.
«It was not known whether any of these vaccines could provide protection
against the new outbreak West African Makona
strain of Ebola Zaire currently
circulating in Guinea,» said John Eldridge, Chief Scientific Officer - Vaccines at Profectus Biosciences, Inc. «Our findings show that our candidate vaccines provided complete, single dose protection from a lethal amount of the Makona
strain of Ebola virus.»
A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed
against the own virus
strain, but also
against different sub-types of HIV that
circulate worldwide.
In preliminary experiments not reported in the Nature paper, Korbinger said he has in vivo evidence that ZMapp works
against the
strain now
circulating in West Africa.
A paper published recently showed that the H3N2 vaccine
strain with egg - based mutations was less able to mount an immune response
against the
circulating H3N2
strain.
There are four
strains circulating in the world, and antibodies for each of the
strains interact with each other in such a way that if a vaccine does not protect
against all forms simultaneously, it could backfire and put a patient at risk of severe disease if exposed to the other types.
The new bivalent vaccine helps protect dogs
against the two
strains of the virus known to be
circulating in the U.S., CIV H3N2 and CIV H3N8.
«Pfizer Animal Health is committed to monitoring swine influenza viruses and bringing to the market vaccines that help protect
against SIV
strains circulating in pork production systems today,» said Kuhn.
Flublok was about 44.6 percent effective
against all
circulating influenza
strains, not just the
strains that matched the
strains included in the vaccine.
The closer the match between the
circulating strains causing disease and the
strains in the vaccine, the better the protection
against influenza.