Now, scientists have modified Salmonella bacteria to trigger a particularly powerful immune response
against human cancer cells implanted in mice, shrinking the tumors and — for the first time — preventing them from metastasizing.
Not exact matches
Hoping to learn something about how the
human body defends itself
against cancer, he had zeroed in on a complex regiment of lymphocytes called T
cells, common to the immune systems in both mouse and man.
The researchers tested the drug combinations
against four different
human cervical
cancer cell lines.
In their latest study, they tested compounds
against cells from nine different types of
human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.
Tests with kidney
cancer and two
human uterine sarcoma
cell lines, one with multidrug resistance, showed that 10 of these new compounds were impressively potent
against all three
cell lines, the researchers reported.
Exploiting the same pre-clinical model used for their studies, the researchers are testing the efficacy of this kind of drug candidates
against cancer stem
cells, and the possibility of identifying combination regimens with standard chemotherapies with minimized toxic effects, with the perspective of their possible application for the treatment of
human breast
cancer.
In research published in BioMetals, UJ3 is shown to be as effective
against human esophageal
cancer cells, as a widely - used chemotherapy drug in use today.
But it's possible that
human cancer treatment might also work
against parasite
cancer cells.
A recently published paper showed that mice with colon
cancer can be «vaccinated» with
human embryonic stem
cells and have a significant immune response
against the
cancer (Li et al., 2009).
He said traditional drugs to treat tapeworm infection — which target the whole organism at the larval stage - might not have been effective
against tapeworm
cancer cells, and it's also unclear whether chemotherapy for normal
human cancer cells could have helped shrink the tumors.
The study relates to a particular type of vaccine (killed)
against a particular virus, influenza, though the findings might hold true for other killed vaccines and for those vaccines consisting only of proteins produced by GM in bacteria, yeast or insect
cells,
against diseases such as hepatitis B (HBV) and
human papilloma virus (HPV, the causative agent of cervical
cancer).
She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of
human gammadelta T
cells as effector
cells of the immune response
against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.
He is the principal investigator of an NCI - funded, multi-million-dollar Specialized Program of Research Excellence (SPORE) in ovarian
cancer, and he is the principal investigator of a multi-million-dollar grant from the New York State Stem
Cell Science program (NYSTEM) to pioneer a novel strategy of reprogramming
human mature T
cells and hematopoietic stem
cells for generating sustained attack
against ovarian
cancer in patients.
And the transfection of the siRNA
against β — catenin resulted in the reduction of miR - 150 expression in the miR -142-3p-expressing
human breast
cancer cells (Figure 5D).
A study published in the Journal of Agriculture and Food Chemistry focused on identifying the means by which fruit extracts or their components provide protection
against human liver
cancer cells.
Studies in animals, and
human cells in laboratory culture, indicate that CLA may protect
against certain types of
cancer (6, 7, 8).
Animal studies and small
human studies suggest that a ketogenic diet protects healthy
cells against anti-
cancer drugs and radiation, while at the same time making
cancer cells more sensitive to the treatment.
This little flower was pitted in a battle royale
against various
human cancer cells.
A tissue culture study of
human breast -
cancer cells found that epigallocatechin gallate, or EGCG, an active compound in green tea, protects
against some forms of breast
cancer by regulating estrogen receptors on breast
cells and inhibiting growth and reproduction of estrogen - dependant breast -
cancer cells.
Mice and
human volunteers who underwent cycles of the Fasting Mimicking Diet had decreased numbers of myeloid
cells, the inflammatory immune
cells that become more numerous as we age, and increased numbers of cytotoxic T
cells, which protect the body
against viruses and
cancer.
According to Lise Alschuler, author of the Definitive Guide To
Cancer: An Integrative Approach to Prevention, Treatment, and Healing, studies on flax lignans demonstrate safety and efficacy in their use against breast cancer, «inhibiting the growth of human estrogen - dependent breast cancer cells in mice and strengthening the tumor - inhibitory effect of tamoxifen&r
Cancer: An Integrative Approach to Prevention, Treatment, and Healing, studies on flax lignans demonstrate safety and efficacy in their use
against breast
cancer, «inhibiting the growth of human estrogen - dependent breast cancer cells in mice and strengthening the tumor - inhibitory effect of tamoxifen&r
cancer, «inhibiting the growth of
human estrogen - dependent breast
cancer cells in mice and strengthening the tumor - inhibitory effect of tamoxifen&r
cancer cells in mice and strengthening the tumor - inhibitory effect of tamoxifen».
A study conducted at the University of California at Santa Barbara found that sulforaphane inhibited the growth of
human breast
cancer cells, causing researchers to praise it is a «promising» protective agent
against breast
cancer.
Enhanced fat burning through green and white tea - brown fat
cells play key role 13.07.2017 Two cups of green tea daily results in more brown fat 25.04.2017 Animal study: half cup of green tea daily is life extending 15.04.2017 Speed up interval - training fat loss with supplement containing caffeine and green tea 19.01.2016 Green tea boosts fat burning after interval training 30.10.2015 Chin - Shin Oolong Tea contains growth hormone booster 02.10.2015 Green tea healthier and more effective on empty stomach 01.09.2015 EGCG speeds up muscle recovery after period of inactivity 19.05.2015 Green tea inhibits breakdown of fast muscle fibres during long - term inactivity 18.05.2015 Five cups of green tea daily rejuvenates skin 10.09.2014 Quercetin boosts inhibitory effect of green tea for prostate
cancer 27.01.2014 Slimming supplement containing ECGC, resveratrol and Grape Seed Extract shown to work in
human study 12.01.2014 Tea protects prostate
against testosterone 10.12.2013 Green tea speeds up muscle recovery after heavy training 11.11.2013 EGCG protects liver and kidneys, and extends life expectancy 04.08.2013 EGCG and caffeine supplement keeps the cold out 26.02.2013 N - oleyl - phosphatidyl - ethanolamine & EGCG combo makes weight - loss diet easier 03.02.2013 Green tea has a slightly anabolic effect on strength athletes 14.01.2013 Cup of green tea with a meal makes it easier to eat less 18.12.2012 Green tea keeps athletes fit as the years go by 24.10.2012 Mushrooms, green tea reduce chance of breast
cancer by factor of 10 13.10.2012 Combination of strength training and green tea gives elderly more muscle mass 12.10.2012 One cup of green tea burns five grams of fat 02.09.2012 Tiny amount of caffeine can burn fat — when combined with tea phenols 27.08.2012 Tea for temporary T boost 24.04.2012 Grow old healthily with green tea 11.03.2012 Tea drinkers have stronger bones 25.02.2012 Lose weight with Pu - Erh tea 17.08.2011 Tea supplement boosts T levels in animal study 30.10.2010 Almost no green tea in green tea sodas 13.10.2010 Drink green tea instead of water — and live longer 24.05.2010 Green tea stackers don't work without exercise 13.05.2010 Metastudy: slimming supplements with green tea do work 27.03.2010 Black tea reduces muscle soreness after training 20.03.2010 Cold brewed white tea contains most antioxidants 04.01.2010 Cup of tea inhibits uptake of mercury from fish 04.12.2009 Polyphenols in juice and tea clear bacteria from your teeth 22.10.2009 Drink three cups of tea a day and add five years to your life 11.09.2009 Bad breath from proteins?
The finding that
human stem
cells may help immunize
against colon
cancer is new and unexpected they added.
The researchers vaccinated mice with
human embryonic stem
cells and found that the mice developed a consistent immune response
against colon
cancer cells.