Not exact matches
Osteocalcin - deficient mice exhibit insulin resistance and
hyperglycemia (27), and administration of undercarboxylated osteocalcin protects
against the metabolic consequences of diet - induced obesity in WT mice (30, 60).
Review of «Human adipose derived stromal / stem cells (hASCs) protect
against STZ - induced
hyperglycemia; analysis of hASC - derived paracrine effectors» from Stem Cells by Stuart P. Atkinson.
«We were interested in investigating how GLP - 1 could protect
against the effects of
hyperglycemia on renal function.»
Through assessment of hASCs potential role in protecting
against STZ ‐ induced
hyperglycemia and loss of β cell mass, the authors have uncovered a novel role for the matrix metalloproteinase inhibitor TIMP ‐ 1 in promoting β cell survival.