In rats, protection
against ischemic injury and improved survival has been demonstrated in both myocardial and cerebral ischemic events.
A possible contributing factor for the cardio protective effects of intermittent fasting is increased levels of adiponectin, a hormone that exhibits both anti-athrogenic and insulin sensitizing effects and has been shown to protect cardiac myocytes
against ischemic injury (44,45).
EPO has now been shown to be protective
against ischemic injury [64] and light damage [16], and the upregulation of EPOR following a recovery period post-hypoxia is likely important in this protection.
Not exact matches
«This finding suggests remote
ischemic preconditioning protected the heart muscle
against injury during bypass surgery, though unfortunately this effect was not associated with improved long - term clinical outcomes,» Hausenloy said.
Dr. Semenza's research interests include the molecular mechanisms of oxygen homeostasis; gene and stem cell therapy for
ischemic cardiovascular disease; the role of HIF - 1 in cancer; and protection of the heart
against ischemia - reperfusion injury.
HIF - 1 also is required for
ischemic preconditioning, short episodes of ischemia and reperfusion that protect the heart
against a subsequent prolonged
ischemic insult.
In an ongoing clinical trial funded by the U.S. National Institutes of Health, 3K3A - APC alone is being given to patients within a few hours of
ischemic stroke (blocked blood flow to the brain), to determine if the protein can help protect
against brain damage.
In many studies, eating whole grains, such as buckwheat, has been linked to protection
against atherosclerosis,
ischemic stroke, diabetes, insulin resistance, obesity, and premature death.