Sentences with phrase «against leukemia cells»

(F) Donor T cells were isolated from recipient spleen on day 14 for CTL assay against leukemia cells.

«Protein isolated from baker's yeast shows potential against leukemia cells: Researchers performed in vitro trials to test the effect of L - asparaginase on acute lymphoblastic leukemia cells and published the results in Scientific Reports.»

Not exact matches

Wapner's narrative follows developments from the recognition of a chromosomal abnormality in cancer cells to the production of a targeted drug against what had been a lethal leukemia.

These engineered cells, called CAR - T cells, were effective for some people against relapses of leukemia over the long term.

Co-senior study investigator and cancer biologist Iannis Aifantis, PhD, says the study offers the first evidence that «drugs targeting and disrupting leukemia cells» microenvironment — or what goes on around them — could prove effective against the disease.»

Discuss how mouse models can be used to study human immune responses against leukemia (using primary or genetically modified leukemia cells) and melanoma

A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life - threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.

CAR T - cell treatment, on the other hand, is being widely tested in children and has shown impressive effectiveness against the most common childhood leukemia, called acute lymphoblastic leukemia.

Enhanced phosphorylation of Nbs1, a member of DNA repair / checkpoint complex Mre11 - RAD50 - Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR / ABL - positive leukemia cells.

This new therapy works well against B - cell acute lymphomblastic leukemia, a cancer of the blood system, which has led the U.S. Food and Drug Administration to expedite approval of the first CAR - T treatment for children and young adults.

In addition, we observed that donor T cells recovered from VPA - treated BMT recipients and controls on day 14 showed comparable cytolytic activity against host - type leukemia cells (Fig. 5F).

A phase I / II trial of genetically modified T cells directed against CD19 for pediatric and young adult patients with relapsed / refractory CD19 + leukemia (NCT02028455).

Using a combination of engineered enzymes and chemical methods, Fasan's lab has further modified micheliolide to develop analogs — or variants — with improved activity against both active leukemia cells and leukemia stem cells.

Stephan's foggy early morning brainwave illuminated an unexpectedly simple approach to making cell - based immunotherapy, in which cancer - targeting immune cells are enlisted to fight tumor cells, as effective against solid tumors as it has been against blood cancers like leukemia.

In 2006, Shelia Gannon was close to the end of a losing battle against acute lymphoblastic leukemia (ALL), a form of cancer that causes abnormal blood formation and a shortage of red and normal white blood cells and platelets.

Direct application of Acai berries onto the leukemia cancer cells kills up to 86 % of them, so it is safe to say that Acai berries are a fighting agent against cancer.

For example, in addition to having about five times more antioxidants, colored rice varieties have shown greater anti-allergy activity in vitro, as well as superior anticancer effects against breast cancer and leukemia cells.

The feline leukemia virus inserts its genetic code into infected cells and can cause various blood disorders which weaken the cat's immune system from protecting against bacteria and viruses found in the everyday environment.