Sentences with phrase «against malaria for»

Not exact matches

While the world has made incalculable gains in the struggle against mosquito - borne diseases, new challenges — like resistance to artemisinin treatments for malaria — are now threatening to turn back the clock.

In the 13 years since he left office, President Clinton has been a relentless and forceful advocate for a number of causes: the fight against HIV / AIDS, malaria, and tuberculosis, and the need to stem greenhouse gas emissions.

In his recent FY2011 budget request, President Obama requested significant funding increases for two of the main programs we have in the fight against malaria: the President's Malaria Initiative (PMI) and the Global Fund to Fight AIDS, Tuberculosis and Mmalaria: the President's Malaria Initiative (PMI) and the Global Fund to Fight AIDS, Tuberculosis and MMalaria Initiative (PMI) and the Global Fund to Fight AIDS, Tuberculosis and MalariaMalaria.

Preliminary results of the study were presented at a World Health Organization (WHO) evidence review group meeting, while UNITAID has issued a call for further research into the use of endectocide class drugs, of which ivermectin is currently the only one registered for human use, as new vector control tools in the fight against malaria and other mosquito borne disease.

The 2015 Nobel Prize in Physiology or Medicine goes to William C. Campbell and Satoshi Ōmura for their discoveries of a medication against roundworm parasites and to Youyou Tu for her discoveries concerning a novel therapy against malaria.

She found that the weakened sporozoites triggered immunity against malaria instead of the disease, paving the way for a potential vaccine.

Professor Dominic Kwiatkowski, one of the lead authors of the paper, from the Wellcome Trust Sanger Institute and the Wellcome Trust Centre for Human Genetics, said: «We can now say, unequivocally, that genetic variations in this region of the human genome provide strong protection against severe malaria in real - world settings, making a difference to whether a child lives or dies.

Researchers have known for decades that the glycophorin cluster of genes is highly variable, but it was not possible to show that this genetic variation was responsible for protecting people against severe malaria.

In recent years, biologists have adapted it as a precise tool for genetic engineering — in scientific experiments, and in prospective genetic - modification strategies against diseases such as malaria.

For instance, one great recent advance in the fight against malaria is a drug called artemisinin.

Did genes for abnormal hemoglobin survive and spread, he wondered, because they protected against malaria infection?

A mutation already well known for conferring protection against a type of malaria appears, paradoxically, to dramatically increase the risk of HIV infection.

Similarly, carriers in the Jackson study of one copy of the genes that cause sickle - cell disease — a useful trait against malaria in Africa — appear to be more at risk for kidney disease.

«For the foreseeable future, artemisinin will be the most powerful weapon in the battle against malaria but, due to its extraction from low - yielding plants, it is currently too expensive to be widely accessible to patients in poorer countries.

«Our idea was to find a way for each individual to create a long - lasting response against malaria,» says Cailin Deal, PhD, who helped lead the research while completing her doctorate at the school.

But as researchers turn to diseases that are more difficult to protect against, such as malaria or HIV, they are setting their sights lower, aiming for vaccines that prevent severe disease but not infection.

A group of insect geneticists, genome researchers, and funding officials has put together a plan to open a new front in the war against malaria: the sequencing of the genome of Anopheles gambiae, the mosquito primarily responsible for spreading the disease in Africa.

In 2002 he learned of the dire need for synthetic artemisinin, a compound derived from the sweet wormwood plant, which is 90 percent effective against the parasite that causes malaria and has few side effects (malaria kills some 3 million people a year).

A human vaccine against malaria has faltered in the face of the sophisticated life cycle of Plasmodium falciparum, the one - celled parasite responsible for the most severe form of the disease.

«As drug resistance is a major problem for malaria control and eradication, it is critical that that we continue to develop new antimalarials that act against previously unexploited targets in the parasite to keep priming the drug pipeline.»

Scientists have been working for decades to develop a vaccine against malaria, but the Plasmodium parasite is a formidable foe.

Most other vaccine trials have tried to use the malaria parasite — rather than the body's reaction against it — to find possible targets for vaccines.

Efficacy against malaria infection of PfSPZ Vaccine administered to infants 5 - 12 months of age in 3 doses by passive and active surveillance for naturally acquired Pf infection, measured by blood smear microscopy, during 6 months following the last vaccine dose.

«What makes it particularly interesting is that the region we can show is associated with protection happens to be right up against a set of genes we know are related to how malaria invades the red blood cell,» study author Dominic Kwiatkowski of the Wellcome Trust Sanger Institute and the Wellcome Trust Centre for Human Genetics told The Post.

It has been known for several decades that exposure to mosquitoes treated with radiation can protect against malaria.

The search for a vaccine against malaria remains high on the global research agenda for many years.

However, until an AMA1 malaria vaccine demonstrates clinical efficacy against genetically diverse natural parasites, the relevance of growth inhibition assays and other humoral and cellular immunogenicity endpoints for clinical development decisions will remain a matter of reasoned conjecture.

They will share the prize with Youyou Tu for her discoveries concerning a novel therapy against malaria.

Safety and efficacy concerns with currently used drugs accentuate the need for new chemotherapeutic options against severe malaria.

Identifying the genetic determinants of phenotypes that impact disease severity is of fundamental importance for the design of new interventions against malaria.

In an interview at the National Institute for Mathematical and Biological Synthesis (NIMBioS), Dr. Ogundahunsi explains how mathematical modeling can help in the fight against malaria, a disease that claimed nearly one million lives in 2008.

For IVIC 2018, the Against Malaria Foundation (AMF) has again been selected as charitable benefactor.

Fundraiser for world swims against malaria.

Richards, R.L., Rao, M., Wassef, N.M., Glenn, G. M., Rothwell, S. W., Alving, C.R. Liposomes containing lipid A serve as an adjuvant for induction of antibody and cytotoxic T - cell responses against RTS, S malaria antigen.

For instance, recent evidence suggests that cultural values of collectivism also serve an «anti-pathogen defence» whereby behavioural manifestations of collectivism, such as conformity and parochialism, function as buffers against the transmission and increased prevalence of disease - causing pathogens (e.g. malaria, typhus and tuberculosis)(Fincher et al. 2008).