Sentences with phrase «against protein antigens»
Learning what they contribute to cell structure, permeability, membrane biogenesis and so on is important in vaccine research because antibodies against protein antigens can disable the protein's function.»
https://www.sciencedaily.com/ Not exact matches
All people have human leukocyte antigens (HLA), proteins that are key to the immune system's defense against bacteria, viruses and other potentially harmful invaders.
*** It is directed against the 5T4 / WAIF1 tumour antigen, a protein found on many different solid tumours and is thought to contribute to the spread of cancer cells.
Confocal images of P150 dystrophic retina transplanted with hNPCctx — GDNF and double stained with antibodies against human nuclear antigen (red) and either (A) recoverin, a photoreceptor and cone bipolar cell marker (green), or (B) protein kinase Cα (PKCα), a bipolar cell marker (green).
The difficulty in using monoclonal antibodies against tumor cells is that most of the antibodies raised will be against immunodominant antigens — all the high - visibility proteins that the immune system recognizes.
Intestinal permeability was assessed by Ussing chamber; epithelial cell (EC) ultra-structure by electron microscopy; RNA expression of genes coding for junctional proteins by Q - real - time PCR; immune response by in - vitro antigen - specific T - cell proliferation and cytokine analysis by cytometric bead array; intestinal microbiota by fluorescence in situ hybridization and analysis of systemic antibodies against intestinal microbiota by surface staining of live bacteria with serum followed by FACS analysis.
When the amino acid sequence is homologous between the target antigen, such as gluten, against which the immune system is mounting a response, and tissue proteins, such as the thyroid tissue, a case of mistaken identity occurs, and the immune response can become directed against self tissues, manifesting as autoimmune disease (Hashimoto's thyroiditis in this instance).
Antibodies against modified food antigens, by reacting with AGEs and tissue proteins, may cause perturbation in degenerative and autoimmune diseases such as diabetes, atherosclerosis, inflammation, autoimmunity, neurodegeneration and neuroautoimmunity.»
Just as certain disease - causing agents or foreign substances will cause the body to produce antibodies against them, certain proteins are known to act like antigens in celiac disease patients, causing the body to produce antibodies against them.
2) Second, these chemicals must bind to our own tissue proteins creating new antigens (an antigen is any substance that causes your immune system to produce antibodies against it, tagging it for destruction and removal).
VANGUARD ® crLyme helps provide broad - spectrum coverage against outer surface protein A (OspA), found in the tick, and contains antigens from multiple types of outer surface protein C (OspC), found in the tick and dog.
She explained that when you give a vaccine antigen, which is the protein of the virus or bacteria you're immunizing against, you actually neutralize any existing antibody directed specifically against that same antigen.