However, it's not easy to design small molecules
against transcription factors
Not exact matches
An entire class of proteins called
transcription factors, which regulate the activity of certain genes by interacting with specific sequences of DNA, has largely been ignored by the pharmaceutical industry because it's difficult to design and screen drugs
against them.
«
Transcription factor may protect
against hepatic injury caused by hepatitis C, alcohol.»
New data suggest that the
transcription factor FOXO3 may protect
against alcohol - induced liver injury.
The Regulatory T - cell
Transcription Factor Foxp3 Protects
against Crescentic Glomerulonephritis.
For example, enterolactone made from flaxseed lignans has been shown to be an estrogen agonist (promoting estrogen production, through increased formation of
transcription factors like ER - alpha and ER - beta), as well as an estrogen antagonist (working
against estrogen production, through inhibition of enzymes like estrogen synthetase).