Sentences with phrase «age of diagnosis declines»

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Approximately 175000 cancer cases are diagnosed annually in children younger than age 15 years worldwide, 1 with an annual increase of around 0.9 % in incidence rate in the developed world, only partly explained by improved diagnosis and reporting.1, 2 Childhood cancer is rare and its survival rate has increased significantly over the years owing to advancement in treatment technologies; however, it is still a leading cause of death among children and adolescents in developed countries, ranking second among children aged 1 to 14 years in the United States, surpassed only by accidents.1, 3 Childhood cancer is also emerging as a major cause of death in the last few years in Asia, Central and South America, Northwest Africa, and the Middle East, where death rates from preventable communicable diseases are declining.2
It is important for physicians and scientists to understand the unique pathology of HS - AGING, and to be able to differentiate it from other diseases, as it is only by making an accurate diagnosis that clinicians can hope to treat people who present with signs of cognitive decline.
The potential for early diagnosis and delaying the onset of motor or cognitive decline by perhaps ten years is of potentially profound importance in an aging society.»
I've written about the use of neuropsychological tests for the differential diagnosis of AD, MCI, normal cognitive aging, and other neurodegenerative diseases, as well as for the prediction of cognitive decline and conversion from MCI to dementia.
We defined adult - onset MDD as a first diagnosis at 17 years or older because (1) this cutoff was consistent with the definition of adult - onset MDD used by Harrington et al2 and (2) the incidence of new cases of depression in this sample spiked between the ages of 15 and18 years and declined thereafter, suggesting that onset of depression at or before age 15 years is unique (Figure 1).27
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