Sentences with phrase «age of disease onset»

If the amount of miRNA were quantified in an HD patient, the amount could provide insight into the likely age of disease onset or life expectancy of the patient which current genetic testing in HD does not provide,» added Myers.

In families affected with SCA1, the number of CAG repeats increases with each generation, correlating with increased severity and an earlier age of disease onset.

Over the following years, he and his colleagues cloned the HD gene, located its stretch of repeated DNA, showed that the size of that stretch is correlated with age of disease onset and age of death, described how it causes disease, and identified genetic factors that affect how quickly symptoms develop.

The overall frequency of this disease in the breed and approximate age of disease onset are unreported for the Cavalier King Charles spaniels.

The high prevalence of the rcd4 mutation within some breeds, along with the typical late age of disease onset, calls for careful consideration as one weighs the importance of rcd4 in a breeding program.

In HD, the length of a person's CAG expansion is a major factor in the age of disease onset.

Genetic testing in a pediatric environment poses unique challenges with respect to age of disease onset, when to test, patient autonomy, etc., and many primary care providers can benefit from education about these issues.

This means no waiting for a dog in question to mature past the age of disease onset to see if it becomes affected, eliminating the need to do test breedings to identify carriers, allows breeders to move toward their goals more rapidly without the setbacks created by inherited diseases.

We know that breeders are concerned about the age of disease onset, and the meaning and implications of late onset when making breeding decisions.