Globorisk measures cardiovascular risk in individuals aged 40 or older by factoring in the person's smoking status, blood pressure, diabetes status, and total cholesterol level, whilst adjusting for the effects of sex and
age on cardiovascular disease between countries.
Not exact matches
Of note, our models may underestimate the true maternal costs of suboptimal breastfeeding; we modeled the effects of lactation
on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before
age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and
cardiovascular disease, 10 we conservatively limited the duration of lactation's effect
on both diabetes and MI.
Overweight and obesity and weight change in middle
aged men: impact
on cardiovascular disease and diabetes
The researchers found that, based
on subjects» genetic profiles, the centenarians could be further divided into 19 subgroups, some of which were associated with delayed onset of
age - related
diseases such as dementia, hypertension and
cardiovascular disease.
They found that the
age of smokers who die from
cardiovascular disease is,
on average, five and a half years younger than people who have never smoked in their lives.
In the most comprehensive study ever
on the impact of smoking
on cardiovascular disease in older people, epidemiologist Dr. Ute Mons from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) analyzed 25 individual studies, compiling data from over half a million individuals
age 60 and older.
In the current study, McKeown and her colleagues analyzed longitudinal data
on 1,685 middle -
aged adults over a period of 14 years, obtained from the Framingham Heart Study's Offspring cohort — a National Heart, Lung, and Blood Institute - funded program that has monitored multiple generations for lifestyle and clinical characteristics that contribute to
cardiovascular disease.
Lloyd - Jones and colleagues examined long - term data
on more than 5,200 men and women
aged 28 to 62 who were free of
cardiovascular disease at the time of their enrollment in the Framingham Heart Study, a decades - long
cardiovascular study.
Lloyd - Jones's editorial is based
on a large new study published in the journal that looked at adults,
ages 50 to 80, with
cardiovascular disease who took extended - release niacin (vitamin B3) and laropiprant (a drug that reduces face flushing caused by high doses of niacin) to see if it reduced heart attack and stroke compared to a placebo over four years.
These subprojects will focus
on aging - associated
diseases (such as Alzheimer's
disease,
cardiovascular diseases, diabetes, muscle weakness) and
on various forms of cancer such as neuroblastoma, colon, or breast cancer.
Between 1970 and 2010, female deaths in this
age group from
cardiovascular disease and diabetes fell
on average by 66 % in 11 affluent countries: Chile, France, Germany, Greece, Japan, New Zealand, Mexico, Poland, the Russian Federation, the United Kingdom and the United States of America, the study showed.
That's because experiments conducted
on the International Space Station involving cells that line the inner surfaces of blood vessels (endothelial cells) show that microgravity accelerates
cardiovascular disease and the biological
aging of these cells.
On average, these patients were more likely to be male, middle -
aged, African - American and have a history of
cardiovascular disease, with a majority taking
cardiovascular medication.
Armed with the knowledge that tooth loss in middle
age can signal elevated
cardiovascular disease risk, adults can take steps to reduce the increased risk early
on, he said.
She directed The Johns Hopkins Center of Excellence for
Aging Research, the Center
on Aging and Health, and the Division of Geriatric Medicine and Gerontology, and led major multidisciplinary research programs
on the causes and consequences of frailty,
cardiovascular disease, cognitive impairment and disability in older adults, and approaches to prevention.
«If we were to view the current findings
on the backdrop of contemporary
cardiovascular risk calculators and statin guidelines, many patients with connective tissue
disease could reasonably consider moderate - intensity statin therapy at
age 35,» he said.
Moreover, PHENONIM - ICS is involved in European projects presenting a strong impact
on human health: Interreg CARDIOGENE (Genetic mechanisms of
cardiovascular diseases), GENCODYS (Genetic and epigenetic networks involved in cognitive dysfunctions), AgedBrainSYSBIO (Basic studies of brain
aging), as well as projects in partnership with industry: MAGenTA (an Industrial Strategic Innovation project supported by Bpifrance about the treatment of major urogenital
diseases) and CanPathPro (H2020 program), to develop a predictive modeling platform of signaling pathways involved in cancers.
They tease apart the influences of
age and
cardiovascular disease (CVD) risk factors
on these cells, whose regenerative capacity has made them the target of much investigation.
It may stave off dementia Among patients with mild Alzheimer's
disease (
age 60 and older), those with lower physical fitness levels (measured by
cardiovascular tests
on a treadmill) had four times more brain shrinkage when compared to normal adults than those who were more physically fit, according to a recent study from the University of Kansas School of Medicine.
Its impact
on cellular function may also interrupt cues for
cardiovascular disease, neurodegenerative
disease and
ageing.
Both avoiding high blood pressure throughout middle
age or delaying the start of the development of high blood pressure seem to have a significant affect
on a person's remaining lifetime
cardiovascular disease risk.
The book provides a deep dive into the relationship between mitochondrial health and
cardiovascular diseases; cardiometabolic syndrome; neurodegenerative
diseases; arthritis; cancer; and the
aging effects
on the skin, eyes, and muscles.
In this episode Rhonda talks about how heat stress from using the sauna makes the body more resilient to the stresses of
aging, possible reasons why one study associated sauna use with up to a 40 % lower all - cause mortality as well as a 50 % lower
cardiovascular disease related mortality, how it enhances athletic endurance, staves off muscle atrophy, improves regrowth of muscle after disuse, and some of the profound effects
on the brain, including the growth of new brain cells, improvement in focus, learning, and memory, and even potentially ameliorating depression and anxiety.
The timing and frequency of these blood tests will depend
on your
age and risk factors or family history for high blood cholesterol or other
cardiovascular diseases such as heart attack or stroke.
Researchers have observed positive results of magnesium
on migraines,
aging, fibromyalgia,
cardiovascular disease, and overall mortality.
His primary focus is
on risk assessment, prevention, and drug - free treatment strategies for
cardiovascular disease and diabetes, as well as general healthy
aging.
On the baseline questionnaires, we requested information about
age; weight and height; smoking status; physical activity; history of diabetes in first - degree relatives; use of postmenopausal hormone therapy; use of oral contraceptives; and personal history of diabetes,
cardiovascular diseases, and cancers.
First, low SES in childhood is a recognized risk factor for
age - related
disease, such as
cardiovascular disease.24 Childhood socioeconomic disadvantage predicts
age - related -
disease risks, such as elevated inflammation levels and the clustering of metabolic risk markers in adulthood.25 - 27 In contrast, the effect of low childhood SES
on later depression risk is debated.28 Second, retrospective investigations and some prospective studies have shown that childhood maltreatment could contribute to
age - related -
disease risks.