Direct evidence that soy isoflavones genistein and daidzein suppress the pituitary - thyroid axis in middle -
aged rats fed 10 mg soy isoflavones per kilo after only 3 weeks as compared with rats eating regular rat chow.
Not exact matches
In one study,
aging rats were
fed blueberries and then given memory tests.
In the 1930s researchers discovered that laboratory
rats fed a limited diet live about 40 % longer than normal and are resistant to many chronic illnesses typical of
aging.
Researchers focused on two pathways that produce energy in muscles, glycolysis (sugar metabolism) and mitochondrial oxidative phosphorylation (OXPHOS) in both young and middle -
aged rats that were
fed a normal diet or a calorie - restricted diet.
To examine the relationships among VF, peripheral, and hepatic insulin sensitivity, we studied 4 - and 18 - mo - old male Sprague - Dawley
rats (n = 42)
fed ad libitum (4 AL and 18 AL) or moderately calorie restricted (18 CR) up to 18 mo of
age.
The question is whether the same low - protein diets that prevent the growth of pre-cancerous lesions once they are formed also increase the toxicity of aflatoxin and other harmful chemicals, decrease the capacity for tissue repair, increase the risk of dying from chemical overdose, and promote the formation of pre-cancerous lesions when these diets are
fed to the
rats of the same strain, sex,
age, and protein requirements.
This would also explain the case of weanling
rats successfully blocking aflatoxin initiation
fed 20 % protein, they were being
fed an adequate amount of protein for their
age, and hence were better at fighting off disease than their protein - starved counterparts.
The researchers
fed blackberries to
aged rats for 8 weeks, after which they tested their ability to perform a series of tasks.
The research team found that the swelling and thus the inflammation were reduced significantly in
rats fed the ketogenic diet regardless of
age.
The researchers» laboratory tests found that
rats fed fructose for a year showed significantly greater
age - related alterations, manifested in their skin and bone collagen.
Compared to
rats fed ad libitum, alternate day fasted
rats showed protection of
age - related changes in dendritic spine number and morphology (20).
Effect of long - term, alternate day
feeding on renal function in
aging conscious
rats.
And a 2000 study in the journal Brain Research found that
aging rats had some of their
age - related memory and motor deficits reversed after they were
fed diets supplemented with spinach, strawberries or blueberries.
One of his earliest studies revealed that alternate - day
feeding made the
rats» brains resistant to toxins that induce cellular damage akin to the kind cells endure as they
age.
Although it is difficult to extrapolate from
rats to humans, we may try to use our results obtained at the tissue level in
rats to interpret our previous observations obtained only at the whole - body level in elderly women (5,6,18), i.e., comparing the responses of liver and muscle protein synthesis to the pulse
feeding pattern in the 2
age groups could suggest that there was also a positive effect of the pulse pattern at the muscle level in humans.
Because there was no significant effect of
age, adult and old
rat data were pooled and comparisons were made by using a two - way ANOVA to discriminate between the effects of protein
feeding pattern (P), nutritional state (N) and their interaction (N × P).
However, protein
feeding pattern was similar at both
ages, i.e., adult
rats consumed 25.3 ± 0.2 % of daily intake (4.46 ± 0.03 g of dry matter) and old
rats consumed 25.1 ± 0.3 % of daily intake (4.22 ± 0.06 g) during the second meal (0800).
Then half of the
rats at each
age were switched to a 11/66/11 / 11 % repartition of daily proteins (pulse pattern) for 21 d. On d 21, epitrochlearis muscle degradation rates were measured in the postabsorptive (PA) or
fed state (PP).
Two groups of
rats were
fed AIN - 76 diet (i.e., control diet, AIN 1977) or the same diet supplemented with 2 g / 100 g
AGE for 4 wk.