Sentences with phrase «aged tissues»

MDI Biological Laboratory Associate Professor James A. Coffman, Ph.D., is studying the regenerative capacity of sea urchins in hopes that a deeper understanding of the process of regeneration, which governs the regeneration of aging tissues as well as lost or damaged body parts, will lead to a deeper understanding of the aging process in humans, with whom sea urchins share a close genetic relationship.

Senescence is associated with normal aging, and senescent cells accumulate in aged tissues, which impair the normal functions of the tissue and contribute to age - related diseases.

Natural lubricants and vitamin E oil can be applied both topically and internally to support ageing tissue.

For setting cancer in the context of ageing tissue, study of normal adult homeostasis is important — we are studying mutational processes, clonal dynamics and cellular competition in thousands of non-cancerous cells and samples from a range of tissue types, in health and disease.

There is a lot of work still to do, and many potential pitfalls before it could be applied to human patients, but in principle almost any illness caused by damaged or ageing tissue — heart disease, diabetes, Alzheimer's and dozens of others — could be fixed this way.

Understanding the molecular mechanisms that control the balance between self - renewal and differentiation in adult stem cells is an important foundation for developing therapies to regenerate diseased, injured or aged tissue.

This approach is rooted in the century - old concept of heterochronic parabiosis, whereby exposure of aged tissues to young factors can extend organismal lifespan and improve aged tissue function.

This mechanism explains the gradual accumulation of cellular and extracellular waste products that poison the microenvironment of aging tissues.

We are focused on the discovery, development and commercialization of cell based therapeutics that prevent, treat or cure disease by repairing and replacing damaged or aged tissue, cells and organs and restoring their normal function.