With a wife and four children at home, DiCarlo was given
aggressive chemotherapy treatment, which didn't work.
After completing a deep review of the literature, he decided to pursue an extremely
aggressive chemotherapy treatment, against the advice of his oncologist.
Not exact matches
Current
treatments for acute lymphoblastic leukemia (ALL), an
aggressive form of blood cancer, include conventional
chemotherapy drugs that inhibit DNA synthesis.
Conventional, high - dose
chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors» recurrence in more
aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered.
In testing multiple HDAC inhibitors in combination with the
chemotherapy drug paclitaxel, known to give some benefit for this
aggressive cancer, they found that class II HDAC inhibitors signal through a newly discovered pathway to promote synergy with
chemotherapy treatment.
Chemotherapy and other cancer
treatments are supposed to get rid of the disease, but a new study finds they can elicit
aggressive tumor growth instead, STAT reports today.
If validated in clinical trials, the signature would help physicians better identify which AML patients would benefit from
chemotherapy and which patients have a prognosis so grave that they may be candidates for more
aggressive treatments such as bone - marrow transplantation.
Based on recent information on the mechanisms of
chemotherapy, a team of researchers of the McGill University Health Centre (MUHC) developed a new clinical approach to increase the efficiency of
treatment in glioblastomas that increased the median survival to 22 months — bringing much needed hope to those affected by this
aggressive disease.
The discovery offers a new
treatment option beyond
chemotherapy for this
aggressive type of breast cancer.
Currently, cancer is present in one in 10 biopsies ordered by physicians, but all must be analyzed by pathologists to identify the extent and volume of the disease, determine if it has spread and whether the patient has an
aggressive or indolent cancer and needs
chemotherapy or a less drastic
treatment.
Of those that had the high - risk signature, cancer spread to the lungs in 55 %, in spite of
chemotherapy treatment, whereas only 10 % of the others showed cancer migration to the lungs — and even then, the lungs were not the principal or most
aggressive site, the team reports 28 July in Nature.
However, as the
treatment involves
aggressive chemotherapy, the researchers stress the procedure carries significant risk.
Weight loss is common during
chemotherapy for
aggressive tumours, both because
treatment may reduce appetite and because tumours lead to muscle wasting.
However, because the
treatment involves
aggressive chemotherapy that inactivates the immune system for a short period of time, some patients died from infections.
But, if a child is classified as high - risk, the survival rate falls to approximately 50 percent even with an
aggressive treatment plan that includes high - dose
chemotherapy, surgery, stem cell transplant, radiation and immunotherapy.
There aren't a lot effective
treatments for this
aggressive disease — it's resistant to most
chemotherapy — and so the need for new approaches is great.
Due to the
aggressive nature of AML, this disease usually requires intensive
treatment, which may include
chemotherapy, radiation therapy, immunotherapy and stem cell transplantation.
A new score that could identify certain women with primary breast cancer in need of more or less
aggressive treatments could play a pivotal role in ensuring they are given the best possible chance of survival, while only giving
treatments such as
chemotherapy when it's necessary.
BUFFALO, N.Y. — Although men with prostate cancer usually respond to standard
treatment with hormone therapy or
chemotherapy, many will eventually experience progression or recurrence despite
treatment — particularly those with high - risk or
aggressive forms of the disease.
Treatment for
aggressive forms of NHL can include
chemotherapy, immunotherapy, radiation therapy, bone marrow transplant, and more.
Doctors wanted to immediately begin «
aggressive» radiation and
chemotherapy and this idea frightened Elaine, as she had seen many family members and friends die from similar
treatments.
One clinical trial with a median follow - up period of 20 years demonstrated that relatively good survival and local control can be achieved in inflammatory breast cancer patients with an
aggressive schedule of alternating
chemotherapy and radiation
treatments.
The notion of a part of the body growing out of control for no apparent reason is bad enough, but the
aggressive and expensive
treatments used for cancer, such as surgery, radiation and
chemotherapy can be frightening as well.
Treatment involved an
aggressive 7 - week course of radiation and
chemotherapy.
Michael subsequently underwent
aggressive chemotherapy and radiation
treatment and was declared tumor - free in January 2011.