Sentences with phrase «aggressive disease»

Unfortunately, doctors currently have no reliable way of predicting which men will develop evidence of worsening or more aggressive disease during active surveillance.

Using this technology it becomes possible to diagnose patients with aggressive disease, predict clinical outcome, and possible anticipate treatment response.

Similarly, a negative MRI is a very good predictor of exclusion of aggressive disease.

In cats, it tends to be a less aggressive disease.

Scientists report learning that each patient with this kind of rare cancer has a unique genetic code that predicts how aggressive the disease is and how sensitive it is to specific treatments.

This choice is challenging, because medical science can not reliably identify those men who are at risk for developing aggressive disease and may benefit from active treatment.

It is a particularly aggressive disease and often beyond the point of effective treatment by the time symptoms appear.

Mast cell disease within the internal organs of cats has a more aggressive disease course.

«In the absence of an Internet librarian, health care professionals should acknowledge that online information on aggressive diseases such as pancreatic cancer could be misleading and potentially harmful, and, thus, they should assume an active role in the evaluation and recommendation of online resources, selecting readable and accurate online resources for their patients, as an instrument to empower patients in the shared decision - making process,» the authors write.

«These findings raise the possibility that by determining the gene expression profile of a patient's tumor, physicians may be able to identify aggressive disease at the outset of diagnosis and start treatment earlier,» said Sungyong You, PhD, an instructor in the Cedars - Sinai Department of Surgery and the first author of the study.

«We thought that if we could understand how some people live several years with this most aggressive disease, we might be able to develop a new therapeutic strategy.»

«Inflammatory breast cancer is a rare and very aggressive disease in which cancer cells block lymph vessels in the skin of the breast.

Loeb says the team next plans further studies to determine why low testosterone levels might trigger aggressive prostate cancer and why maintaining normal levels may protect against aggressive disease.

The researchers also reasoned that if erectile dysfunction medications cause melanoma, they would expect to find more aggressive disease among people who take the medications, but that was not the case.

In the study, researchers found that, as a group, men prescribed testosterone for longer than a year had no overall increase in risk of prostate cancer and, in fact, had their risk of aggressive disease reduced by 50 percent.

«Ovarian cancer researchers find biomarker linked to prognosis in aggressive disease type.»

Given the role of Msi in promoting aggressive disease, the investigators partnered with Robert MacLeod PhD, vice-president of oncology drug discovery at Ionis Pharmaceuticals, to develop next - generation antisense oligonucleotide (ASO) inhibitors against Msi.

Hypoxia, or a lack of oxygen, is one example of a phenomenon that should weaken the tumor, but instead, the malignant cells are able to compensate and drive more aggressive disease behavior.

The Maharaj Institute is helping those who are seriously ill regain their natural immune ability to fight and overcome aggressive diseases such as cancer, chronic inflammatory and autoimmune diseases and disorders associated with aging.

It is prescribed primarily for patients with persistent aggressive disease who have failed other available DMARDS.

This incredibly aggressive disease can be treated, but almost all dogs who suffer from it eventually succumb to it.

For reliable diagnosis of aggressive disease, he said, «we need to have panels, not just rely on a single metabolite.»

«Men found to have aggressive disease at the time of prostatectomy could be offered additional treatment with radiation therapy to prevent recurrence, while sparing men with slow - growing tumors,» adds Chakravarti, who holds the Max Morehouse Chair of Cancer Research.

Drugs targeted at the microRNA could knock out the effects of multiple cancer - causing mutations at once, while tests for it could identify patients with the most aggressive disease, the researchers believe.

«It would help spare patients with indolent disease from unnecessary treatments and their side effects and aid in the diagnosis and directing patients with aggressive disease to the appropriate treatment.»

Mutations in the beta - catenin gene, or flaws in the factors that degrade it, have long been linked to more aggressive disease in various tumor types, including colon, lung and prostate cancer, and melanoma.

Prof. Severine Vermeire (KU Leuven / UZ Leuven): «In the future, gut bacteria may be used to help identify PSC patients with a more or less aggressive disease, or patients that may benefit from microbiota - based therapies, such as fecal microbiota transplantation or targeted pre - and probiotics.»

«Further, these subtropical drylands are home to aggressive diseases such as dengue and schistosomiasis.

Genetic Causes of a Type of Pancreas Cancer Uncovered Researchers deciphered the genetic causes of a type of pancreas cancer known as neuroendocrine or islet cell tumors and uncovered a unique genetic code specific to each patient that predicts how aggressive the disease is and how well it will respond to specific treatments.

AML is an aggressive disease of malignant immature blood cells which, if left untreated, almost always causes the death of the affected patient.

«Once they block this first pathway, then other pathways can get activated, leading to an even more aggressive disease.»

In 2014, new combination therapies to treat patients with metastatic melanoma hit the market, helping extend the lives of those with this aggressive disease.

Preclinical findings revealed that Myb gives immune cells called regulatory T (Treg) cells the «authority» to control the strength of the immune response depending on the level of «threat», from minor infections to aggressive diseases.

Although there are several ways to remove RB from the cellular machinery, the group found that complete loss, rather than inactivation, of the RB gene was associated with changes in gene - networks closely linked to aggressive disease.

«We propose that inhibiting miR - 194 could reduce rates of metastasis in patients with aggressive disease, but the development of a drug to achieve this goal is still a long way off.»

«Using this combination therapy to treat patients with such an aggressive disease could be an important advance in keeping patients alive and well for longer.»

«Building upon previous data related to the PRSS1 mutations found in patients with early - onset pancreatitis, we learned that combined with our current data, patients with PRSS1 are more likely to have an aggressive disease course,» said Giefer.

«Fusion biopsy will tell us with much greater accuracy than conventional biopsy whether or not they have aggressive disease.»

The authors stressed that the long - term reduction in aggressive disease was observed only in men after more than a year of testosterone use, and the risk of prostate cancer did not differ between gels and other types of preparations.

Aspirin does not appear to be protective or associated with improved clinical outcomes or survival among breast cancer patients with aggressive disease, the researchers of one study report.

«The fact that men in 2013 who presented with metastatic disease had much higher PSAs than similar men in 2004 hints that more aggressive disease is on the rise,» Schaeffer said.

«Metastatic prostate cancer cases skyrocket: More lax screening rather than more aggressive disease?.»

A team of researchers led by UC San Francisco scientists has identified a new drug target for triple - negative breast cancer, an aggressive disease subtype that has the poorest outcomes and accounts for as many as one in five cases.

Researchers developed a new clinical approach to increase the efficiency of treatment that increased the median survival to 22 months — bringing much needed hope to those affected by this aggressive disease.

Although Lacks died shortly afterwards from her aggressive disease, scientists were able to keep her cancer cells alive and replicating under laboratory conditions.

Based on recent information on the mechanisms of chemotherapy, a team of researchers of the McGill University Health Centre (MUHC) developed a new clinical approach to increase the efficiency of treatment in glioblastomas that increased the median survival to 22 months — bringing much needed hope to those affected by this aggressive disease.

This week, a team at Cold Spring Harbor Laboratory (CSHL) publishes encouraging results of a pilot study testing a new way of pinpointing the minority who have aggressive disease at the time of diagnosis, a fact that usually determines whether they will have surgery or not.

«Importantly, it points us to a potential new treatment avenue for pancreatic cancer, an aggressive disease that's often caught in the later stages.