Sentences with phrase «aggressive disease at»

This week, a team at Cold Spring Harbor Laboratory (CSHL) publishes encouraging results of a pilot study testing a new way of pinpointing the minority who have aggressive disease at the time of diagnosis, a fact that usually determines whether they will have surgery or not.

«These findings raise the possibility that by determining the gene expression profile of a patient's tumor, physicians may be able to identify aggressive disease at the outset of diagnosis and start treatment earlier,» said Sungyong You, PhD, an instructor in the Cedars - Sinai Department of Surgery and the first author of the study.

Not exact matches

Mothers of 66 children who had celiac disease but didn't know it yet reported more child anxiety and depression, withdrawn behavior, aggressive behavior, and sleep problems when compared to the more than 3,651 mothers of children who did not have celiac disease at all.

Researchers at the Universities of Bristol and Oxford found that testing asymptomatic men with PSA detects some disease that would be unlikely to cause any harm but also misses some aggressive and lethal prostate cancers.

«Because the disease is so aggressive, patients may receive no treatment at all or if they are given an option it will be for just one line of treatment, so it's essential that the most suitable treatment is identified quickly.

A new, aggressive strain of yellow rust, a fungal disease of wheat, is waiting in the wings, and east Africa isn't the only region at risk.

Women with the variant were at much higher risk for cancer, had more recurrences, were often hit with multiple cancers and were more likely to die from aggressive forms of these diseases.

Scientists at Cedars - Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk.

This choice is challenging, because medical science can not reliably identify those men who are at risk for developing aggressive disease and may benefit from active treatment.

Study coauthor Ronald Levy, an oncologist at the Stanford University School of Medicine, says that physicians generally take their cues from the disease, waiting to see how fast it is moving — and treating it with toxic chemotherapy (sometimes with radiation) only if it becomes aggressive.

Most people with Alzheimer's disease and other memory - affecting conditions also get aggressive, agitated, depressed, anxious, or delusional from time to time, says senior author Helen C. Kales, M.D., head of the U-M Program for Positive Aging and Geriatric Psychiatry at the University of Michigan Health System and investigator at the VA Center for Clinical Management Research.

Seventy - five percent of these cases are classified as high grade serous type, and they show more advanced disease at diagnosis and are more aggressive.

Given the role of Msi in promoting aggressive disease, the investigators partnered with Robert MacLeod PhD, vice-president of oncology drug discovery at Ionis Pharmaceuticals, to develop next - generation antisense oligonucleotide (ASO) inhibitors against Msi.

Rather than the body's immune system destroying its own tissue by mistake, researchers at the University of Bristol have discovered how cells convert from being aggressive to actually protecting against disease.

In the era of personalized cancer therapy, patients with TNBC remain at considerably higher risk of relapse and death than patients with other breast cancer subtypes, due to the aggressive nature of TNBC and the lack of newer targeted therapies for the disease.

«Prostate cancer can often be an indolent disease, where a patient may only require surveillance rather than aggressive surgery,» noted co-author Christopher J. Kane, MD, professor of urology at UC San Diego.

As this variant also appears to be associated with the development of more aggressive prostate tumors, a diagnostic test for the variant may enable doctors to make more informed decisions as to how closely they should monitor those who are at high risk, and how aggressively they should treat the disease once it presents.

The research ideas you develop at the workshop should: • Lead to the significant advancement of our understanding of sensor technologies suitable for liquid biopsy • Consider the practical challenges of low volume liquid usually taken for analysis and the inconsistency of sample preparation across point of care sites • Prioritise biomarkers with high specificity for cancer or even for multiple cancer types, including markers specific to cancers that will become aggressive as opposed to non-lethal disease

Men with BRCA1 / 2 mutations who develop prostate cancer tend to develop these cancers at an earlier age than average and may develop more aggressive forms of the disease.

Men with these mutations are more likely than non-carriers to contract aggressive, lethal prostate cancer, to be diagnosed at a more advanced stage and to ultimately die of the disease, researchers say.

Carriers of germline mutations in BRCA2 have at least five times greater risk of prostate cancer and frequently develop a more aggressive form of the disease.

I think we all agree that we over treat prostate cancer in this country compared to what you see in Europe with similar outcomes and so but I think this is where the human or the Cancer Genome Project or at least better biomarkers for looking at mutations that we already know occur in these diseases I think hopefully within the next few years every single patient who is diagnosed with prostate cancer those biopsies will be characterized and then the patients followed, hopefully watchful waiting and we'll ultimately get a correlation between what mutational events predict a rather dormant disease as opposed to a very aggressive disease.

While men with the more aggressive form of the cancer make up about 5 % of the 180,000 to 200,000 cases of prostate cancer in the U.S. each year, and only 12 % will have these mutations, that population is still at considerably higher risk of developing advanced disease.

«Studies show that people who are low in vitamin D are at greater risk of developing MS, as well as having more frequent relapses and a more aggressive progression of the disease,» Kalb says.

And a study released in March 2008 by researchers at the University of Texas M.D. Anderson Cancer Center in Houston showed that obese and overweight women also had lower breast cancer survival rates and a greater chance of more aggressive disease than average - weight or underweight women.

«Now rheumatologists are more aggressive at treating the diseases — because we can be,» he says.

One reason may be that men in the study seemed to develop Alzheimer's at a younger age than women and had a more aggressive form of the disease.

The tumors are very aggressive and metastatic, so it is a fair assumption that at the time of diagnosis the disease will have already spread beyond the primary site.

For the safety of your pet and other guests at Pet Paradise, we do not accept pets in heat, pets that have been coughing within the last week, pets that have open wounds or stitches, pets that are recovering from surgery, pets that have contagious diseases, or pets who are people - aggressive.

Transmitted primarily via bite wounds, free - roaming aggressive cats are at highest risk for this disease.

It soon became obvious that only the very old, very ill, severely injured, or aggressive dogs were to be euthanized at the SPCA and that no animals would die for lack of space or because they had treatable diseases or behavior problems.

Add in injuries, parasites, infections and such and assume that every dog you take in is a potential vector for the spread of diseases into any new home, and at risk of medical meltdown or will get aggressive to defend itself.

But that is not an \ «unpredictable \» trait, & they are not human aggressive at all, unless there is something wrong with them (abuse, training, or disease / ailment.)

Rabid dogs in local communities are killed as soon as they're identified, but not all rabid dogs exhibit the classic frothing at the mouth and aggressive behavior that are the obvious signs of the disease.

Children growing up in such aggressive families may believe that family aggression is acceptable and thus become more likely to behave in aggressive or harmful ways toward others.12 13 On the other hand, neglectful parents tend to show minimal physical affection towards their children, know little about child development and have incompetent caretaking skills14 which can put their children at a higher risk for obesity and other diseases.