Not exact matches
In clinical trials the treatment — which involves extracting individual patients» immune T - cells, modifying them to seek out tell - tale biological markers associated with blood cancers like aggressive lymphoma, and then pumping those modified killer cells back into the body — has shown major promise, in some cases eliminating all signs of the cancer in patients six months after treatmen
In clinical trials the treatment — which involves extracting individual patients» immune T - cells, modifying them to seek out tell - tale biological markers associated with blood cancers like
aggressive lymphoma, and then pumping those modified killer cells back into the body — has shown major promise,
in some cases eliminating all signs of the cancer in patients six months after treatmen
in some cases eliminating all signs of the cancer
in patients six months after treatmen
in patients six months after treatment.
In December, Juno presented positive preliminary data on JCAR017 in patients with r / r aggressive non-Hodgkin lymphoma (NHL), reporting an 80 % overall response rate and a 60 % complete response rat
In December, Juno presented positive preliminary data on JCAR017
in patients with r / r aggressive non-Hodgkin lymphoma (NHL), reporting an 80 % overall response rate and a 60 % complete response rat
in patients with r / r
aggressive non-Hodgkin
lymphoma (NHL), reporting an 80 % overall response rate and a 60 % complete response rate.
«This is wonderfully serendipitous — our drug just happens to be able to overcome both of the biological mechanisms that are key to survival of
aggressive lymphoma,» Dr. Melnick says, adding that the inhibitor completely eradicated DLBCL
in mice
in a short time, with no detectable side effects.
In the journal Cell Reports, published today online, the scientists describe how the powerful master regulatory transcription factor Bcl6 regulates the genome, ensuring that
aggressive lymphomas survive and thrive.
The most common type of non-Hodgkin
lymphoma in adults, DLBCL is an
aggressive cancer that can develop
in many types of tissue.
Every year, nearly 2,000 people
in Switzerland are diagnosed with
lymphoma, a disease that can be very
aggressive, resisting standard treatments with chemotherapeutic drugs.
Mantle cell
lymphoma is a very
aggressive and difficult to treat cancer originated
in blood cells and lymph nodes.
For example, a drug called ibrutinib has been tested
in clinical trials to treat an
aggressive form of non-Hodgkin
lymphoma, diffuse large B - cell
lymphoma (DLBCL).
This causes genomic instability
in developing immune cells and,
in the absence of a working tumor suppressor protein such as p53, an
aggressive form of
lymphoma develops
in mice.
New research published online
in Blood Journal of the American Society of Hematology (ASH), challenges the generally held belief that individuals with HIV and
aggressive lymphoma are not candidates for standard treatment.
Scope: 22 institutions Treatment: CD19 - targeting CAR T - cell therapy Results: 42 % of patients with
aggressive large B - cell
lymphoma remained
in remission after 15 months
Sixty percent of all NHL cases
in the United States are
aggressive NHL, with the most common subtype being diffuse large B - cell
lymphoma (DLBCL).
The use of anti-CD19 chimeric antigen receptor T cells induced a nearly sixfold higher rate of complete response compared with historical outcomes
in patients with refractory,
aggressive non-Hodgkin
lymphoma.
Surveillance computed tomography (CT) is usual practice for patients with
aggressive non-Hodgkin
lymphoma (aNHL)
in complete remission (CR).
This is compared to Peripheral T cell
lymphoma which is much more
aggressive, seen
in Boxers and Aussies.
Low - grade small cell
lymphoma of the intestinal tract
in cats is a less
aggressive form of
lymphoma.
Malignant
Lymphoma This
aggressive type of cancer occurs
in the lymph nodes and can be fatal.
George Goldner and Nancy Krieg brought Nemo to Cornell's large animal hospital
in 2013 for treatment of
lymphoma, an
aggressive blood cancer.