Sentences with phrase «aggressive meningiomas»
«Aggressive meningiomas are very insidious tumors.
https://www.ucsf.edu/
The new study found significant hypermethylation in the most aggressive meningiomas, and showed that these DNA modifications specifically silenced genes that usually inhibit FOXM1 expression and Wnt signaling.
Raleigh's team found that a gene named FOXM1 was at the heart of aggressive meningioma growth, and a signpost of subsequently poor clinical outcomes, including death.
The researchers also identified new links between aggressive meningioma proliferation and activation of an intercellular signaling pathway called Wnt — which typically plays a role during embryonic development and tissue formation.
Not exact matches
The panel also called for «aggressive research» on using RU486 and other drugs in the antiprogrestin class as contraceptives and as treat - ment for endometriosis, uter - ine fibroids, advanced breast cancer and meningioma brain tumours.
However, approximately twenty percent of meningiomas are aggressive and can recur even after surgery and radiation therapy.
Together, these findings suggest that hypermethylation may be an early trigger that leads to the development of aggressive forms of meningioma.