Sentences with phrase «aggressive phenotype»

In support of this notion, KLF4 has been found to be frequently overexpressed in 70 % of breast cancers, and its localization in the nucleus of breast cancer cells has been identified as a marker of aggressive phenotype in early - stage infiltrating ductal carcinoma (30).

Nuclear localization of KLF4 is associated with an aggressive phenotype in early - stage breast cancer

Mutations in fms related tyrosine kinase 3 (FLT3) gene are the most common mutations found in acute myeloid leukemia (AML) and are characterized by an aggressive phenotype with a high prevalence of relapse.

First, because DNA was available only in adulthood, we can not establish when chronic physical aggression became associated with the observed methylation patterns and whether they precede or follow the appearance of the aggressive phenotype.