An epidemiological study of people in Northern Italy reported that vitamin C intake has «possible protective activity» against skin cancer202 and greater consumption of antioxidants was associated with less
aggressive prostate cancer in the United States.203 A 2014 systematic review by Chinese researchers concluded that low doses of vitamins, specifically vitamins A, C and E, can significantly reduce the risk of stomach cancer.204
This resulted in a higher absolute number of
aggressive prostate cancers in the dutasteride group than in the placebo group — even though the placebo group had a higher rate of prostate cancer.141 Thus, as we have seen elsewhere, e.g., rofecoxib (Vioxx ®), celecoxib (Celebrex ®), balance in biological processes is more beneficial than absolute interruption.)
This resulted in a higher absolute number of
aggressive prostate cancers in the dutasteride group than in the placebo group — even though the placebo group had a higher rate of prostate cancer.145 (See above «Mechanisms through which 5α - reductase inhibitors promote prostate cancer»)(Neal, please make this a link to this section above) Thus, as we have seen elsewhere, e.g., rofecoxib (Vioxx ®), celecoxib (Celebrex ®), balance in biological processes is more beneficial than absolute interruption.)
Not exact matches
«Markers for
prostate cancer death can identify men
in need of more
aggressive treatment.»
Eating a diet higher
in saturated fat, a type of fat found commonly
in foods such as fatty beef and cheese, was linked to more
aggressive prostate cancer, a study by University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators has
cancer, a study by University of North Carolina Lineberger Comprehensive
Cancer Center researchers and collaborators has
Cancer Center researchers and collaborators has found.
«Genetic association with
aggressive prostate cancer discovered: Study showed a threefold increase
in the risk of
aggressive prostate cancer for men with the genetic mutation..»
An international study published
in the Journal of the National
Cancer Institute has identified a genetic connection to the aggressive form of prostate c
Cancer Institute has identified a genetic connection to the
aggressive form of
prostate cancercancer.
«Why
prostate cancer is more
aggressive in obese patients.»
In a new study published in The Journal of Urology ®, researchers determined that men who followed a Mediterranean diet, rich in fish, boiled potatoes, whole fruits, vegetables, legumes, and olive oil, and low consumption of juices had lower risk of aggressive prostate cancer (PC) than those who followed other dietary patterns like Prudent or Western diet
In a new study published
in The Journal of Urology ®, researchers determined that men who followed a Mediterranean diet, rich in fish, boiled potatoes, whole fruits, vegetables, legumes, and olive oil, and low consumption of juices had lower risk of aggressive prostate cancer (PC) than those who followed other dietary patterns like Prudent or Western diet
in The Journal of Urology ®, researchers determined that men who followed a Mediterranean diet, rich
in fish, boiled potatoes, whole fruits, vegetables, legumes, and olive oil, and low consumption of juices had lower risk of aggressive prostate cancer (PC) than those who followed other dietary patterns like Prudent or Western diet
in fish, boiled potatoes, whole fruits, vegetables, legumes, and olive oil, and low consumption of juices had lower risk of
aggressive prostate cancer (PC) than those who followed other dietary patterns like Prudent or Western diets.
But although the drug, called finasteride, caused a 25 % reduction
in prostate cancer, it also boosted the risk of
aggressive prostate cancer among those diagnosed with the disease.
«A more complete Mediterranean diet may protect against
aggressive prostate cancer: New study
in The Journal of Urology ® finds that a high intake of fruits, vegetables, and whole grains might not be enough.»
Of greater concern were the higher rates of
prostate cancer classified as
aggressive: It developed
in 6.4 % of the men
in the finasteride group, compared with 5.1 %
in the placebo group.
A Northwestern University - led study
in the emerging field of nanocytology could one day help men make better decisions about whether or not to undergo
aggressive prostate cancer treatments.
«Emotional distress may motivate men with low - risk
prostate cancer to choose more
aggressive treatment, such as choosing surgery over active surveillance,» said UB's Heather Orom, the lead author on the study, published
in the February issue of the Journal of Urology.
In the group of patients with
aggressive, or high risk,
prostate cancer, the average number of days from diagnosis to surgery or radiation treatment was 96 days for Caucasian patients, and 105 days for African American patients.
The authors stressed that the long - term reduction
in aggressive disease was observed only
in men after more than a year of testosterone use, and the risk of
prostate cancer did not differ between gels and other types of preparations.
In the study, researchers found that, as a group, men prescribed testosterone for longer than a year had no overall increase in risk of prostate cancer and, in fact, had their risk of aggressive disease reduced by 50 percen
In the study, researchers found that, as a group, men prescribed testosterone for longer than a year had no overall increase
in risk of prostate cancer and, in fact, had their risk of aggressive disease reduced by 50 percen
in risk of
prostate cancer and,
in fact, had their risk of aggressive disease reduced by 50 percen
in fact, had their risk of
aggressive disease reduced by 50 percent.
The old idea that
cancer is less
aggressive in the elderly is not entirely without merit: breast and
prostate cancers tend to grow more slowly
in older patients.
Researchers have discovered that a marker found on
aggressive prostate cancer cells could also be used as a way to guide treatments to the cancer, according to new research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Live
cancer cells could also be used as a way to guide treatments to the
cancer, according to new research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Live
cancer, according to new research presented at the National
Cancer Research Institute (NCRI) Cancer Conference in Live
Cancer Research Institute (NCRI)
Cancer Conference in Live
Cancer Conference
in Liverpool.
«These genes are found
in between 6 and 14 % of men» said Alexandre Zlotta, «This makes it one of, if not the, most common genes yet found to be associated with
aggressive prostate cancer.
The new technology led to the diagnosis of an
aggressive prostate cancer located
in an area normally not visible using the ultrasound machine alone.
«
In some cases, a low volume of less aggressive prostate cancer may not necessitate treatment, but even in those cases where a «treatment» is not performed in favor of active surveillance, the emotional distress of a cancer diagnosis shouldn't be underestimated,» Turini sai
In some cases, a low volume of less
aggressive prostate cancer may not necessitate treatment, but even
in those cases where a «treatment» is not performed in favor of active surveillance, the emotional distress of a cancer diagnosis shouldn't be underestimated,» Turini sai
in those cases where a «treatment» is not performed
in favor of active surveillance, the emotional distress of a cancer diagnosis shouldn't be underestimated,» Turini sai
in favor of active surveillance, the emotional distress of a
cancer diagnosis shouldn't be underestimated,» Turini said.
In addition, research continues to uncover new clues to identify which men are at highest risk of
aggressive prostate cancer and could most benefit from screening and treatment.
'' (
In the context of prostate cancer) there's a big interest in trying to find biomarkers to discriminate between aggressive and nonaggressive disease,» said Renny Franceschi, U-M professor of dentistry, biological chemistry and biomedical engineerin
In the context of
prostate cancer) there's a big interest
in trying to find biomarkers to discriminate between aggressive and nonaggressive disease,» said Renny Franceschi, U-M professor of dentistry, biological chemistry and biomedical engineerin
in trying to find biomarkers to discriminate between
aggressive and nonaggressive disease,» said Renny Franceschi, U-M professor of dentistry, biological chemistry and biomedical engineering.
A new study published online by Science links chronic fatigue syndrome to a possibly contagious rodent retrovirus, XMRV, which has also been implicated
in an
aggressive form of
prostate cancer.
In unrelated studies, other researchers have linked XMRV — again controversially — to an
aggressive form of
prostate cancer.
As if chronic fatigue syndrome (CFS) hasn't caused enough brawls, a new study published online by Science links the disease to a possibly contagious rodent retrovirus, XMRV, which has also been implicated
in an
aggressive form of
prostate cancer.
Like pervasive hypertension, some
cancers, such as
prostate and breast, tend to occur earlier and be more
aggressive in blacks than whites, said Dr. Edward J. Kruse, chief of surgical oncology at MCG and the Georgia
Cancer Center.
The latest studies suggest that a man's BRCA status can be an important piece of information, especially at a time when many doctors are taking a less
aggressive stance
in screening and treating
prostate cancer.
PSMA is overexpressed
in prostate and increases
in its expression
in the
aggressive forms of
prostate cancer.
Mutations
in the beta - catenin gene, or flaws
in the factors that degrade it, have long been linked to more
aggressive disease
in various tumor types, including colon, lung and
prostate cancer, and melanoma.
Carriers of germline mutations
in BRCA2 have at least five times greater risk of
prostate cancer and frequently develop a more
aggressive form of the disease.
Professor Ros Eeles from the Institute of
Cancer Research and The Royal Marsden, who co-leads the prostate cancer ICGC study with Professor Colin Cooper from the ICR and Professors David Neal and Douglas Easton from The University of Cambridge, said: «One of the major challenges in treating prostate cancer is determining who needs aggressive treatment — some are slow growing and will never need treatment whilst others will develop qu
Cancer Research and The Royal Marsden, who co-leads the
prostate cancer ICGC study with Professor Colin Cooper from the ICR and Professors David Neal and Douglas Easton from The University of Cambridge, said: «One of the major challenges in treating prostate cancer is determining who needs aggressive treatment — some are slow growing and will never need treatment whilst others will develop qu
cancer ICGC study with Professor Colin Cooper from the ICR and Professors David Neal and Douglas Easton from The University of Cambridge, said: «One of the major challenges
in treating
prostate cancer is determining who needs aggressive treatment — some are slow growing and will never need treatment whilst others will develop qu
cancer is determining who needs
aggressive treatment — some are slow growing and will never need treatment whilst others will develop quickly.
Men who carry heterozygous deleterious germline mutations
in BRCA2 are predisposed to
aggressive prostate cancer (1 — 4).
I think we all agree that we over treat
prostate cancer in this country compared to what you see in Europe with similar outcomes and so but I think this is where the human or the Cancer Genome Project or at least better biomarkers for looking at mutations that we already know occur in these diseases I think hopefully within the next few years every single patient who is diagnosed with prostate cancer those biopsies will be characterized and then the patients followed, hopefully watchful waiting and we'll ultimately get a correlation between what mutational events predict a rather dormant disease as opposed to a very aggressive di
cancer in this country compared to what you see
in Europe with similar outcomes and so but I think this is where the human or the
Cancer Genome Project or at least better biomarkers for looking at mutations that we already know occur in these diseases I think hopefully within the next few years every single patient who is diagnosed with prostate cancer those biopsies will be characterized and then the patients followed, hopefully watchful waiting and we'll ultimately get a correlation between what mutational events predict a rather dormant disease as opposed to a very aggressive di
Cancer Genome Project or at least better biomarkers for looking at mutations that we already know occur
in these diseases I think hopefully within the next few years every single patient who is diagnosed with
prostate cancer those biopsies will be characterized and then the patients followed, hopefully watchful waiting and we'll ultimately get a correlation between what mutational events predict a rather dormant disease as opposed to a very aggressive di
cancer those biopsies will be characterized and then the patients followed, hopefully watchful waiting and we'll ultimately get a correlation between what mutational events predict a rather dormant disease as opposed to a very
aggressive disease.
Research shows how signaling by an immune system component appears to play an important role
in driving particularly
aggressive prostate cancer...
Roswell Park
Cancer Institute researchers have identified a gene that influences metastasis in prostate cancer, and may help clinicians to identify aggressive prostate tumors before they progress and spread to other o
Cancer Institute researchers have identified a gene that influences metastasis
in prostate cancer, and may help clinicians to identify aggressive prostate tumors before they progress and spread to other o
cancer, and may help clinicians to identify
aggressive prostate tumors before they progress and spread to other organs.
Leigh Ellis, PhD, and colleagues at Roswell Park Comprehensive
Cancer Center (Roswell Park) have identified two genes that appear to be simultaneously overexpressed
in aggressive prostate cancers resistant to the androgen - targeted treatments enzalutamide and abiraterone acetate.
His laboratory is interested
in understanding the role of metabolic adaptations
in breast and
prostate cancer progression, and elucidating mechanisms that promote therapy resistant
aggressive metastatic disease.
A study was done
in 2013 which proved that patients who had poor sleeping habits were much more likely to develop an
aggressive form of
prostate cancer.
While men with the more
aggressive form of the
cancer make up about 5 % of the 180,000 to 200,000 cases of
prostate cancer in the U.S. each year, and only 12 % will have these mutations, that population is still at considerably higher risk of developing advanced disease.
In a report published in the New England Journal of Medicine, scientists say that a panel of 20 genes can distinguish the more common localized prostate cancer that grows slowly and rarely spreads from the more aggressive type that can spread quickl
In a report published
in the New England Journal of Medicine, scientists say that a panel of 20 genes can distinguish the more common localized prostate cancer that grows slowly and rarely spreads from the more aggressive type that can spread quickl
in the New England Journal of Medicine, scientists say that a panel of 20 genes can distinguish the more common localized
prostate cancer that grows slowly and rarely spreads from the more
aggressive type that can spread quickly.
The findings also hint that
in coming years, it may be possible to use the panel not just among men with advanced disease but to distinguish between men who develop the slower growing type of
prostate cancer from the more
aggressive type.
Considering the side effects and adverse results of
prostate cancer treatment, these new results may help some men make the choice to forgo
aggressive treatment
in lieu of less invasive options.
The task force also calls for more research
in this area, including ongoing studies looking at the potential for MRI and genetic testing to better detect
aggressive prostate cancers, Krist added.
In the
Prostate Cancer Prevention Trial, a study involving more than 18,000 men, subjects taking dutasteride had a lower rate of prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placeb
Prostate Cancer Prevention Trial, a study involving more than 18,000 men, subjects taking dutasteride had a lower rate of prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placebo
Cancer Prevention Trial, a study involving more than 18,000 men, subjects taking dutasteride had a lower rate of
prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placeb
prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placebo
cancer, but a significantly higher rate of
aggressive prostate cancers than the placeb
prostate cancers than the placebo group.
However, recent studies show a correlation between low levels of DHT and decreased survival
in prostate cancer patients, rendering this assumption highly questionable.16, 17, 18, 19 According to one recent paper, «Low dihydrotestosterone
in the
prostate is probably sufficient to propagate the growth of
aggressive prostate cancer.»
In the
Prostate Cancer Prevention Trial, a study involving more than eighteen thousand men, subjects taking dutasteride had a lower rate of prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placeb
Prostate Cancer Prevention Trial, a study involving more than eighteen thousand men, subjects taking dutasteride had a lower rate of prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placebo
Cancer Prevention Trial, a study involving more than eighteen thousand men, subjects taking dutasteride had a lower rate of
prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placeb
prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placebo
cancer, but a significantly higher rate of
aggressive prostate cancers than the placeb
prostate cancers than the placebo group.
But then a friend was diagnosed with a very
aggressive form of
prostate cancer and I got involved
in helping rehab his pelvic floor through what I knew from teaching women.
Not to mention that fish oil could result
in «
aggressive»
prostate cancer.