Not exact matches
Bruce Buchholz of the Lawrence Livermore National
Laboratory used cellular markers for a study
in which he concluded that we're more or less stuck with the number of fat
cells we have at about
age 20.
Reporting their
laboratory findings
in the journal
Aging, the team observed that addition of DPI to a mixed population of
cells eliminated the tumour initiating cancer stem
cells.
«This lets us keep
age - related signatures
in the
cells so that we can more easily study the effects of
aging on the brain,» says Rusty Gage, a professor
in the Salk Institute's
Laboratory of Genetics and senior author of the paper, published October 8, 2015
in Cell Stem
Cell.
The funds will help the clinic establish
laboratories to study senescent
cells, which seem to accumulate
in our bodies with
age.
A series of new mouse models have recently been developed
in the
laboratory that will allow us to dissect how DNA damage, oxidative stress and chromatin remodeling impact on mitochondrial integrity and stem
cell decline during
aging.
Another is to monitor the effects of transplanting telomerase - deficient but ex vivo telomere - extended bone marrow into late - generation, TMM - disabled mice, so as to be certain that the niche of such animals (or, by implication,
aging humans) will support the homing, engraftment, and initial development and differentiation of such cells; the necessary research is underway now thanks to a SENS Foundation grant to Dr. Zhenyu Ju of the Institute of Laboratory Animal Sciences and Max - Planck - Partner - Group on Stem Cell Aging in the Chinese Academy of Medical Sciences, and research partner of prominent telomere biologist Dr. K. Lenhard Rud
aging humans) will support the homing, engraftment, and initial development and differentiation of such
cells; the necessary research is underway now thanks to a SENS Foundation grant to Dr. Zhenyu Ju of the Institute of
Laboratory Animal Sciences and Max - Planck - Partner - Group on Stem
Cell Aging in the Chinese Academy of Medical Sciences, and research partner of prominent telomere biologist Dr. K. Lenhard Rud
Aging in the Chinese Academy of Medical Sciences, and research partner of prominent telomere biologist Dr. K. Lenhard Rudolph.
«The notion that the stem
cell microenvironment is
aging will certainly influence how we think about using stem
cells in regenerative medicine,» says Leanne Jones, Ph.D., an assistant professor
in the
Laboratory of Genetics who led the study.