«We initiated the Great Ape Aging Project 20 years ago because we saw
an aging chimpanzee population under human care that would need geriatric attention for disorders similar to those affecting aging humans,» said Joseph Erwin, Ph.D., research professor of anthropology at the George Washington University.
By examining brain regions most affected by Alzheimer's disease pathology in humans, the group demonstrated that amyloid beta plaques and blood vessels were present in all 20
aged chimpanzee brains.
Researchers from Kent State University's College of Arts and Sciences, along with colleagues from the George Washington University, Yerkes National Primate Research Center, Georgia State University, Barrow Neurological Institute and the Icahn School of Medicine at Mount Sinai, found that the brains of
aged chimpanzees, our closest living relatives, show pathology similar to the human Alzheimer's disease brain.
«Pathologic hallmarks of Alzheimer's found in
aged chimpanzee brains.»
«The presence of amyloid and tau pathology in
aged chimpanzees indicates these Alzheimer's disease lesions are not specific to the human brain as generally believed,» Hof continued.
Kent State University researchers analyzed the brains of
aged chimpanzees to show pathology similar to the human Alzheimer's disease brain.
Publication:
Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease.
«We initiated the Great Ape Aging Project 20 years ago because we saw
an ageing chimpanzee population under human care that would need geriatric attention for disorders similar to those affecting ageing humans,» said Dr. Joseph Erwin, research professor of anthropology at the George Washington University.
The brains of
aged chimpanzees, our closest living relatives, show pathology similar to the human Alzheimer's disease (AD) brain, according to a new, multi-institution research study.
Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease.
Not exact matches
Jane Goodall, a bona fide interesting person, left her home in England and moved to Tanzania at
age 26 to begin studying
chimpanzees.
Rushmore collected information about the traits of individual
chimpanzees including
age, sex, rank and family size.
By comparing it with that of modern humans,
chimpanzees and bonobos, plus Neanderthals and Denisovans, Meyer estimated its
age at 400,000 years, twice as old as our own species and far older than any hominin genome previously sequenced (Nature, DOI: 10.1038 / nature12788).
Scientists from the department of social neuroscience at the Max Planck Institute for Human Cognitive and Brain Sciences (MPI CBS) together with colleagues from the MPI for Evolutionary Anthropology (MPI EVA) explored the question at what
age we develop the motivation to watch, from our perspective, a deserved punishment and if this feature also exists in our closest relatives —
chimpanzees.
The findings from humanity's closest relatives could help researchers to understand why people develop dementia, as well as suggest that caretakers of
aging, captive
chimpanzees watch them closely for behavioural changes.
He eventually found refuge on Black Beauty Ranch in Texas, where he died, at an early
age for a
chimpanzee, in 2000.
THE MEANING «This is an important paper because it provides evidence for the minimum
age of the
chimpanzee behavior of cracking nuts with stone tools,» says Stanley Ambrose, an anthropologist at the University of Illinois at Urbana - Champaign.
Chimps have never been known to flake rocks intentionally to fashion tools, but Mercader believes that way back during a «
chimpanzee Stone
Age,» they did crack nuts with the stones found close to the Noulo site.
The
chimpanzees rated were
aged 8 to 48, a majority had been captive born and mother - raised, and all had lived at the facility for at least two years.
For long - lived species such as humans,
chimpanzees, whales and some birds, longer survival is associated with higher reproductive rates and a loss in fertility only at an extremely old
age.
Working in the lab of Salk's Fred Gage, the Vi and John Adler Chair for Research on
Age - Related Neurodegenerative Disease, Narvaiza, Marchetto and their colleagues identified genes that are differentially expressed between iPSCs from humans and both
chimpanzees and bonobos.
The orphaned and mother - reared
chimpanzees matched in
age and sex.
In an earlier study at Gombe (Tanzania), immature female
chimpanzees were also observed to pay closer attention to their mothers using tools and became proficient tool users at an earlier
age than males.
Aging of the cerebral cortex differs between humans and
chimpanzees.
Brain
aging in humans,
chimpanzees (Pan troglodytes), and rhesus macaques (Macaca mulatta): magnetic resonance imaging studies of macro - and microstructural changes.
Age - related effects in the neocortical organization of
chimpanzees: gray and white matter volume, cortical thickness, and gyrification.
If the
chimpanzee aging profiles approximate the patient mitochondrial disease profiles, then this will provide strong evidence that
aging is a mitochondrial disease.
To further explore the mitochondrial hypothesis of
aging, we propose to study the
chimpanzee, our closest relative.
Research shows that
chimpanzees approaching the level of Stone
Age people.
While the relationship between
age and brain atrophy in humans is well documented and could potentially bias a comparison between different
age groups, there is no evidence that this is the case in dogs (a recent study has shown that Labradors in the
age groups 1 — 5, 5 — 10 and 10 + have similar cerebellar volumes)[22] or even
chimpanzees [25].