Sentences with phrase «agonist drugs»

Because inhalers often contain concentrated doses (often 200 doses in one small vial) of beta - agonist drugs (e.g., albuterol) or steroids (e.g., fluticasone), dogs that bite into them are exposed to massive amounts of the drugs all at once.

CAFO beef and poultry has many disadvantages, including fewer of the most valuable nutrients found in organically - raised meats, while being contaminated with hormones, antibiotics, beta - agonist drugs, and pesticides.

In the National Institutes of Health - funded study, researchers at Wake Forest Baptist identified and evaluated six rare gene variants within the beta2 - adrenergic receptor gene, the gene that may influence the response to beta agonist drugs.

«Rare genetic variations may account for life - threatening reaction to long - acting beta agonist drugs in some people.»

Not exact matches

In the past, researchers have looked into how one component of the experimental drug — GLP - 1 receptor agonists — affects people with Alzheimer's disease and Parkinson's disease.

Key findings presented at AACR included sustained peripheral NK and T cell expansion, doses were well - tolerated and the drug candidate's role as a long - acting CD122 agonist without targeting CD25.

Breastfeeding should be encouraged in women who are stable on their opioid agonist, who are not using illicit drugs, and who have no other contraindications, such as HIV infection (73, 74).

OCA is the first in a new class of drugs, farnesoid X receptor (FXR) agonists, and the response of the patients to OCA shows that abnormalities in the system it targets may be critical for this condition.

A team including Roth and Brian Shoichet, a chemist at the University of California, San Francisco, who uses computer simulations to find new drugs, last year published details of a powerfully G - protein - biased µ - receptor agonist, PZM21.

Three distinct classes of drugs: dopaminergic agonists (such as D - amphetamine), serotonergic agonists (such as LSD), and glutamatergic antagonists (such as PCP) all induce psychotomimetic states in experimental animals that closely resemble schizophrenia symptoms in humans.

The researchers showed that a two - day treatment regimen with partial or selective PPAR - γ agonists (Telmisartan and Rosiglitazone — both FDA - approved drugs) ameliorated the pathological outcomes of infection in mice by inducing expression of glucose transporters.

Medical options also have improved substantially, with the availability in recent years of new classes of diabetes drugs such as GLP - 1 (glucagon - like peptide - 1) receptor agonists and SGLT2 (sodium - glucose co-transporter-2) inhibitors.

By the time patients are diagnosed with it, they have most likely already tried drugs known as beta - agonists that relax the airways to ease breathing, with disappointing results.

Many of the people who take current asthma drugs, called beta - 2 agonists, become less sensitive to them.

These drugs are Dopamine agonists because they bind to the dopamine receptors, and help with dopamine - mediated functions (dopamine being one of the chemicals that is severely in the Parkinsonian brain).

Furthermore, the drug was characterized as agonist of casein kinases 1 (CK1); however, this effect was not confirmed and in colon cancer cells there was no correlation between PPAM toxicity and mutations in Wnt signaling mediators [57, 58].

«Weinberg's work is different because the drug, called an OX40 agonist, boosts positive signals to T cells.

As an agonist of the GLP - 1 receptor, Exendin - 4 is a potent stimulator of insulin secretion and has a much longer half life than GLP - 1 (~ 2 minutes) making it a suitable drug candidate for the treatment of obesity and type - 2 diabetes.

Selective 5 - hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: Identification of drugs in several animal models of CNS related disorders.

And drugs called gonadotropin - releasing hormone agonists can shrink the tumors, though they are linked to side effects similar to menopause, such as hot flashes.

GABA agonists can be produced in or out of the body and can include anything from drugs to other naturally occurring substances.

A 2013 study on rats at the University of Michigan Health System suggests tart cherries provide similar benefits as a class of drugs called PPAR agonists, which are medications prescribed for metabolic syndrome, a group of symptoms that present a cardiovascular risk.

The long - term use of these drugs increases stroke risk, but amazingly, the cherries reduced the risk of stroke when they were administered with the PPAR agonists.

Other medication options include anti-anxiety drugs, antidepressants and gonadotropin - releasing hormone agonists.

Common pharmaceuticals range from opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) to α2 - agonists, gabapentin, amantadine, ketamine, and local anesthetics.

Recommended combinations for such injections include α2 - adrenoceptor agonists, opioids, and dissociative drugs.