Sentences with phrase «agonist used»

Butorphanol tartrate, also known as Torbutrol ® is an opiate agonist used by veterinarians primarily as an anti-tussive, to help alleviate coughing.

In 2005 the FDA approved Requip, a dopamine agonist used to treat Parkinson's disease, for the treatment of moderate to severe RLS.

Not exact matches

Breastfeeding should be encouraged in women who are stable on their opioid agonist, who are not using illicit drugs, and who have no other contraindications, such as HIV infection (73, 74).

As an intern at Smith Kline and French in Philadelphia, Pennsylvania, Bowen was a medicinal chemist, charged with finding a more selective agonist — an active binding agent — to be used in a spray to treat asthmatics.

Indeed, our bodies use endo - cannabinoids in much the same way as they use opioids in the central nervous system: as synapse agonists and antagonists.

«Countries using these measures should instead increase the availability of proven opioid - agonist therapies, such as methadone, and ensure there is adequate access to voluntary treatment programs in community settings and facilitate people with opioid addiction to seek treatment.»

«The results are relevant for clinical use of specific antibodies or related inhibitors in IL - 17RA dependent severe asthma, suggesting equal efficacy using either agonist or receptor blockade to treat severe asthma crisis,» said Ryffel.

A team including Roth and Brian Shoichet, a chemist at the University of California, San Francisco, who uses computer simulations to find new drugs, last year published details of a powerfully G - protein - biased µ - receptor agonist, PZM21.

Most currently used testosterone regulators are GnRH agonists, which stimulate GnRH receptors rather than blocking them, causing an initial surge in testosterone production before lowering the hormone's levels in the body.

A total of 2489 adults with COPD on tiotropium (TIO), long - acting beta - agonist inhaled corticosteroids (LABA / ICS), and / or short - acting bronchodilators (SAB) alone or in combination were studied using retrospective data from the COPDGene study and prospective data from the telephone and web - based biannual Longitudinal Follow - Up program.

While biased agonists may be able to be used more safely at higher doses than other opioids, it remains to be seen how other side effect profiles will be affected.

In the new study, the researchers used rodent models to compare this kind of «biased» KOR agonist, called triazole 1.1, and a conventional KOR agonist.

The researchers found that the addition of vitamin D3 to ciclesonide did not significantly reduce the rate of first treatment failure (a composite outcome of decline in lung function and increases in use of beta - agonists, systemic steroids, and health care utilization) compared with placebo; 28 percent and 29 percent of participants in each group, respectively, experienced at least 1 treatment failure during 28 weeks.

Positive or neutral effects have been seen in bone metabolism with the use of DPP - 4 inhibitors and GLP1 receptor agonists.

We believe that this new information on the structure of the adiponectin receptors will help us understand new relationships between the structure and functions of these important receptors, which we know to be evolutionarily conserved, and hopefully will contribute to the development of new adiponectin receptor agonists that can be used for the treatment of obesity - related diseases such as type 2 diabetes.

Women using short - acting reliever medication (known as beta - agonists) took 20 % longer to conceive on average.

As for beta2 agonists, an analysis of 26 studies found no significant benefits to athletes but competitors still use them extensively (hence the large number of positive tests).

The researchers demonstrated the method by using it to find a potent antibody mimic, or «agonist,» of erythropoietin (EPO), a hormone that stimulates the production of red blood cells.

In addition to a range of antibodies, Abcam offers over 4,000 pharmacological tools covering receptor agonists and antagonists, like Tamoxifen Citrate and oestrogen receptor, which is also used in the control of gene expression.

He previously showed that in comparison to white children, a higher percentage of minority children are not helped by inhaled asthma rescue medicines, called beta - agonists, used to rapidly re-open airways during asthma episodes.

Other research is investigating whether agonist reagents that can signal various immune cells such as T cells, dendritic cells, or NK cells, through the TNF family receptors OX40, 4 - 1BB, HVEM, or LTβR can be used to increase natural immune responses to viruses or tumors that might lead to new strategies for vaccination.

Due to the serious side effects caused by the activation of the pharmacologically and structurally closely related subtypes, it is essential that 5 - HT2C agonists developed for clinical use have a high specificity and subtype selectivity.

Using sazetidine - A as a template, medicinal chemists developed multiple series of novel ligands with modifications to the pyridine core, azetidine ring, and alkynyl side chain with the objective of designing α4β2 - nAChR partial agonists of high specificity.

Dopamine agonists have been on the market for about 15 years and were originally used as Parkinson's medication before they had FDA approval for RLS use.

A: Dopamine agonists have been on the market for about 15 years and were originally used as Parkinson's medication before they had FDA approval for RLS use.

In particular, the medications known as short - acting beta2 - agonists (a type of bronchodilator) can provide quick relief from asthma symptoms — but they can also be damaging if they are used too often.

Using short - acting beta2 - agonists too often is a sign that asthma is out of control.

However, for people who do not have a tumor, or in specific cases, medications such as somatostatin analogues or dopamine agonists that suppress growth hormone secretion may be used.

The long - term use of these drugs increases stroke risk, but amazingly, the cherries reduced the risk of stroke when they were administered with the PPAR agonists.

Most of these Olympians used inhalers (beta 2 - agonists), which dilate the bronchial passageways into the lungs to improve their breathing.

It is created to support the optimal function of specific hormones through the use of hormone specific adaptogens, hormone specific agonists and hormone specific functional mimetics.

Like agonist activation, antagonist co-activation is generally measured using EMG amplitudes.

The use of these agonists in the treatment of cocaine addiction has also shown promising results4.

EMG amplitudes are often used to measure agonist muscle activation in order to:

EMG amplitudes are also used to draw inferences about agonist muscle activation.

Using the strict definition, voluntary activation refers to the percentage of involuntary force production that can be exerted by an agonist muscle group, most commonly using the interpolated twitch technique (Shield & Zhou, 2Using the strict definition, voluntary activation refers to the percentage of involuntary force production that can be exerted by an agonist muscle group, most commonly using the interpolated twitch technique (Shield & Zhou, 2using the interpolated twitch technique (Shield & Zhou, 2004).

Even though there are substantial problems with using EMG amplitudes to measure changes in agonist muscle activation over time, it is not uncommon for researchers to use it in this way.

Electric potential difference in muscles is most often studied using EMG in relation to agonist muscles performing either isometric or dynamic movements but it can also be measured in both agonist and antagonist muscles, in order to study co-activation (Fee & Miller, 2012).

Many patients experience mild toxicosis seen as excessive lethargy for one or two days after dipping.8 More overt signs of toxicosis are similar to those seen with the use of alpha2 - adrenergic agonists, including sedation, hypothermia, bradycardia, and hyperglycemia.

Buspirone (BuSpar ® or Bespar) is the only 5 - HT agonist that's used regularly in companion animal behavior treatment plans.

For especially resistant cases of incontinence, estrogens and alpha - adrenergic agonists can be used together.

Another choice is to use a medicine known as a serotonin agonist, which can sometimes be useful at the beginning of SSRI treatment.