Sentences with phrase «agouti mice»

The most well known example is that of the Agouti mice: they are yellow, fat and are prone to diabetes and cancer.

In Martin's view, the result strongly suggested that the patients had inherited the silenced gene from one of their parents, like the case with agouti mice.

Typically, when agouti mice breed, most of the offspring are identical to the parents: just as yellow, fat as pincushions, and susceptible to life - shortening disease.

They started with pairs of fat yellow mice known to scientists as agouti mice, so called because they carry a particular gene — the agouti gene — that in addition to making the rodents ravenous and yellow renders them prone to cancer and diabetes.

With no more than a change in diet, laboratory agouti mice (left) were prompted to give birth to young (right) that differed markedly in appearance and disease susceptibility.

Not exact matches

Normally, to achieve such a rapid evolutionary shift, a species needs to start with an alternative version of a gene already in circulation, giving natural selection more to work with, but in deer mice the new version of Agouti spread rapidly from a standing start.

Agouti viable yellow mice might have something to say about the human obesity epidemic.

Up to this point, the best way to study epigenetic effects has been a strain of mice known as agouti viable yellow.

Jirtle is well known for his work on mice that carry the agouti gene, which is highly vulnerable to environmental influences.

The researchers then used a technique called optogenetics to stimulate specific neurons — the agouti - related peptide neurons (AgRP)-- known to induce food consumption in sated mice.

To identify genes whose expression correlated with adiposity, we profiled gene expression in perigonadal adipose tissue from 24 mice in which adiposity varied due to sex, diet, and the obesity - related mutations agouti (Ay) and obese (Lepob).

The expression of more than 12,000 transcripts in parametrial and epididymal adipose tissue was monitored in C57BL / 6J mice whose body mass varied secondary to sex, diet, or mutations in the agouti (Ay / +) or leptin (Lepob / ob) loci.

Effect of dietary carbohydrate source on the development of obesity in agouti transgenic mice

There are insectivorous bats, raccoons, coatimundis (quash), rats and field mice, paca (Agouti paca, locally the gib nut).