Sentences with phrase «airway cell cultures»

Not exact matches

Human nasal epithelial cells, cultured on a microchip, react to air pollutants just like they would in the upper airway.

«We compared the ability of RSV and parainfluenza virus (PIV3)-- another common virus in children that causes much less severe airway disease — to infect and cause inflammatory responses in a cell culture model of human epithelial cells, which compose the lining of the lung airway.

A newly developed aerosol deposition chamber also allowed for the particles to be realistically deposited on cell cultures from healthy and diseased airways.

Microscopic images show that RMC - 1 prevented FOXM1 from entering the nucleus in cultured human airway epithelial cells and in mouse allergen - sensitized respiratory airways.

The research team then tested RMC - 1 in cultured human airway epithelial cells and mouse models of asthma (via injection into the animals» peritoneal cavities).

The engineered cell culture enabled interaction between three cell types of the airways and reproduced their physiological interfaces — becoming essentially an «organ - on - chip.»

The cellular model of the airway mucosa could provide insight into biological and pathophysiological effects that conventional cell cultures or animal models do not capture, and help lead to the development of new therapeutics.

«The microfluidic cell cultures reproduced functions of the airway tissues such as mucus secretion and acted as a barrier to molecules,» said Katelyn Sellgren, Ph.D., a postdoctoral research scientist at RTI and first author of the paper.