Demonstration of loss of heterozygosity by single - nucleotide polymorphism microarray analysis and alterations in strain morphology in Candida
albicans strains during infection.
Not exact matches
There are over 300 different
strains of candida,
albicans just happens to be the most common in breastfeeding dyads.
Antifungal drugs can be used to decrease and control C.
albicans in the gut and prevent it from spreading to the bloodstream, but repeated use of antifungal drugs can lead to drug resistant -
strains of fungal pathogens.
Specifically, Micro-8 will assess gene expression, morphology and virulence responses of a yeast
strain, Candida
albicans (C.
albicans), following exposure to spaceflight.
Many
strains of pathogenic yeast, such as Candida
albicans (C.
albicans) can develop resistance to these drugs.
Because the compound is metabolized too rapidly for study in mice, the team mimicked its effects by knocking out cytochrome B in C.
albicans and infecting mice with this mutant
strain.
The genetic mutations that enable certain
strains of C.
albicans to resist AmB simultaneously render it highly susceptible to environmental stressors and disarm its virulence factors.
While antibiotics effectively kill both pathogenic and beneficial bacterial
strains with the exception of antibiotic - resistant species of streptococcus and other
strains, they do not affect the many forms of yeast such as Candida
albicans naturally found in the body in a nondominant role.
The results show that caprylic and capric acids cause the fastest and most effective killing of all three
strains of C.
albicans tested, leaving the cytoplasm dis - organized and shrunken because of a disrupted or disintegrated plasma membrane».
Some specialist laboratories are even able to identify the different species of candida present, and such a result could be quite significant, as some
strains have a tendency to be harder to eradicate (such as candida tropicalis) than candida
albicans.
[1] There are many
strains of candida, but the most common is candida
albicans.