Sentences with phrase «aldehyde dehydrogenase»
Aldehyde dehydrogenase is an enzyme that carries out an important chemical reaction in our bodies. It helps to convert toxic chemicals called aldehydes into less harmful substances. This enzyme plays a crucial role in maintaining our overall health by removing these harmful compounds from our system. Full definition
Nakano and colleagues found that one form of the enzyme aldehyde dehydrogenase — ALDH1A3 — is a specific marker for mesenchymal GSCs, and his group is the first to show that, among the heterogeneous mix of cells in a GBM tumor, cells with high levels of ALDH1A3 expression were more tumorigenic in vivo than are cells that are low in ALDH1A3.
sciencedaily.com
They found that cyclophosphamide kills all of the donor's transplanted bone marrow cells except for stem cells containing high levels of an enzyme called aldehyde dehydrogenase (ALDH).
Currently, she is investigating how inhibiting aldehyde dehydrogenase can kill ovarian cancer stem cells by inducing necroptosis.
PPAM inhibited mammosphere formation of aggressive breast cancer cells and decreased expression of the CSC surrogate marker aldehyde dehydrogenase (ALDH1) as well as of the epithelial - mesenchymal transition (EMT) phenotype [59].
They also had 32 % more betaine aldehyde dehydrogenase, a compound found to reduce chromosomal abnormalities in human blood exposed to radiation.
This allows for the identification, evaluation, and isolation of stem and progenitor cells based on aldehyde dehydrogenase (ALDH), expression and not their cell surface phenotype.
Your gender Adding insult to injury: In women, the enzyme aldehyde dehydrogenase (ALDH)-- which breaks down alcohol in the stomach — can work less efficiently than in men, says Scott Walters, PhD, associate professor at the University of Texas School of Public Health.
That study found that benomyl inhibited an enzyme called aldehyde dehydrogenase (ALDH), which converts aldehydes highly toxic to dopamine cells into less toxic agents, and therefore contributed to the development of Parkinson's.
The antialcoholism medication disulfiram (Antabuse) inhibits aldehyde dehydrogenase (ALDH), which results in the accumulation of acetaldehyde upon ethanol ingestion and produces the aversive
More recently, aldehyde dehydrogenase 1 (ALDH1) has been identified as a new CSC marker, and the cells isolated by this marker partially overlap with previous identified CSC population (3).
The variant encodes an amino acid change in ALDH16A1, a member of the aldehyde dehydrogenase (ALDH) superfamily, and could motivate further biological studies of this pathway.
Adding insult to injury: In women, the enzyme aldehyde dehydrogenase (ALDH)-- which breaks down alcohol in the stomach — can work less efficiently than in men, says Scott Walters, PhD, associate professor at the University of Texas School of Public Health.
These include the flavin monooxygenases (FMOs are responsible for detoxifying nicotine from cigarette smoke); alcohol and aldehyde dehydrogenases (metabolize alcohol), and monamine oxidases (MAOs break down serotonin, dopamine, and epinephrine in neurons).