High - fat diet induced neuropathy of pre-diabetes and obesity: effects of «healthy» diet and
aldose reductase inhibition.
Not exact matches
«The discovery that
aldose reductase regulates mucus production and goblet cell metaplasia makes
inhibition of this enzyme an attractive therapeutic option to reduce mucus - related airway obstructive diseases — and for the first time gives us a real chance to alter the course of the underlying disease in asthma and COPD.»
[13] Mechanisms that may account for lipoic acid's benefit in preventing diabetic complications include prevention of protein glycosylation [14] and
inhibition of the enzyme
aldose reductase, the latter of which subsequently inhibits conversion of glucose and galactose to sorbitol.