"Alkaline phosphatase" refers to an enzyme that helps break down molecules in our bodies. It plays a role in various bodily functions, such as digestion and bone growth.
Full definition
Abnormal liver tests consist of mild - to - moderate elevations of ALT and AST but marked elevation of serum
alkaline phosphatase levels, reflecting interference with bile drainage.
Genetic Studies of Blood Group - Associated Variations in a Human Serum Alkaline Phosphatase
(Improved bone health markers have included a decrease in the number of cross-linked telopeptides and a decrease in blood levels of bone
specific alkaline phosphatase.)
Blood tests may show red blood cells that are abnormally sized, varying white blood cell count levels, the loss of red blood cells, and an increase in the
enzyme alkaline phosphatase.
Low dietary intake of copper may also be associated with increased fecal free radical production and fecal
water alkaline phosphatase activity, risk factors for colon cancer.
The researchers then explored the biological applications of their nanocrystals by using them to
detect alkaline phosphatases, enzymes that frequently indicate bone and liver diseases.
When these building blocks interact with a cervical cancer biomarker known as glycosylphosphatidylinositol - anchored
placental alkaline phosphatase, or GPI - anchored PLAP, which is located on lipid rafts, they self - assemble into nano - scale chains, or «nanofibrils», that glue lipid rafts into large clusters.
In animals harboring intraperitoneal hollow - fiber or subcutaneous implants containing light - inducible transgenic cells, the serum levels of the human glycoprotein
secreted alkaline phosphatase could be remote - controlled with fiber optics or transdermally regulated through direct illumination.
BrdU staining (
using alkaline phosphatase bound secondary antibody) was performed on whole corneas plus scleral rims exposed to BrdU antibodies on the endothelial side whereas BrdU fluorescence (using fluorescein bound secondary antibody) was obtained from transverse sections of the these tissues by the same procedure.
«Having a quantifiable ctDNA was also associated with measure of higher disease burden such as a higher PSA, higher lactic acid dehydrogenase, and a
higher alkaline phosphatase,» Chi said.
The cells also exhibited significantly greater albumin transport, glucose reabsorption, and brush
border alkaline phosphatase activity.
It stimulates the production of calcitonin, the hormone responsible for inhibiting cells (osteoclasts) that breaks bone down and
activates alkaline phosphatase, an enzyme that forms new calcium crystals in bones.
One should also consider hepatic lipidosis when the cat's
blood alkaline phosphatase level is significantly above normal as well, particularly in cats that refuse to eat.
Solter PF, Hoffmann WE, Hungerford LL, Peterson ME, Dorner JL: Assessment of corticosteroid -
induced alkaline phosphatase isoenzyme as a screening test for hyperadrenocorticism in dogs.
In addition, iPS cells stained positive
for alkaline phosphatase (AP) activity, which is a prototypical marker for ES cells (Figure 2D).
Other data obtained in this report (BrdU nitroblue tetrazolium staining
by alkaline phosphatase and fluorescence due to fluorescein) would further suggest that putative stem cells are located in the posterior limbus between the peripheral endothelium and the trabecular meshwork.
They found that the levels of a bone formation marker known as bone -
specific alkaline phosphatase (BSALP) and a bone resorption marker known as tartrate - resistant acid phosphatase (TRACP) fell during hibernation, suggesting that overall bone turnover had decreased, the team reports online today in The Journal of Experimental Biology.
Low dietary copper increases fecal free radical production, fecal
water alkaline phosphatase activity and cytotoxicity in healthy men.
Test subjects» body weights, as well as hemoglobin, packed cell volume,
serum alkaline phosphatase and serum albumin are measured.
Prognosis of patients with this disease depends on multiple factors, the most commonly cited including: presence of metastasis (negative),
elevated alkaline phosphatase (negative), large tumor size (negative), humerus location (negative), treatment chosen (dogs receiving amputation and chemotherapy have improved survival times over dogs receiving amputation alone) 1.