Sentences with phrase «allele of a single gene»

First, unlike CRISPR, the AAV - based approach is only able to target a single allele of a single gene at once.

Not exact matches

In the U.S., this behavioral division follows a genetic one: workers bearing two copies of one form, or allele, of the Gp - 9 gene live in nests governed by a single matriarch, whereas those that have one copy or a pair of a second allele take orders from a female oligarchy.

Reviewing thousands of genome wide associate studies (GWAS) to identify genetic variants in single nucleotide polymorphisms (SNPs), investigators at Dartmouth's Norris Cotton Cancer Center found that some alleles (one of a pair of genes located on a specific chromosome) are more frequently risk - associated with disease than protective.

Further analysis revealed that a single - letter change in the gene accounted for 46 per cent of the population's hair colour variation, with the blonde allele being recessive to the dark hair allele.

For one thing, each chromosome contains tens of thousands of different genes (or rather, alleles of different genes), and it will still be quite a few years before you can specify each single gene.

Because of these limitations, the AAV approach is best suited for tissue culture based approaches that require modification of only a single allele of a gene, such as the introduction of heterozygous endogenous epitope tags, or the introduction of dominant mutations of a gene into the endogenous allele in cultured cells.

Here we present a rapid genome - wide approach capable of identifying multiple genetic drivers of medically relevant phenotypes within malaria parasites via a single experiment at single gene or allele resolution.

It is well known that purebred dog breeds are associated with differing susceptibility to specific malignancies, suggesting that selected breeds of dog are inheriting «at risk» alleles for very few genes, perhaps even a single gene, with a profound effect.

However, while the few studies that have analyzed the issue do not agree on the incidence of ridgelessness within the breed, they all show a ridgeless rate significantly lower than 25 %, which can not be explained using the Punnett square model for single gene / two allele inheritance.