Sentences with phrase «alleles from»

At the present time, an insufficient number of the countries from this correlation are represented in the genetic databases [e.g. HapMap (International HapMap Consortium, 2005) and Human Genome Diversity Panel (Li et al., 2008)-RSB- to determine if the present results are significantly different from the frequency distribution of randomly selected alleles from representatives of each of these countries.
This social construction of the self may function akin to an implicit social support network (Kim et al., 2008) that is likely to buffer individuals with social sensitivity alleles from the adverse consequences of stress and improve life satisfaction.
This tells us that heritability contributes to risk, and so it may be possible to reduce the incidence by eliminating the highest risk alleles from the population.
The gradual loss of alleles from populations is known as «genetic drift», this is a random process which occurs naturally in all populations; it may not matter much in the large gene pool of a large population, but becomes increasingly serious over time in the small gene pools of smaller populations.
It represents the chance that a dog will inherit a homozygous pair of alleles from an ancestor on both sides of the pedigree, or that a given percentage of a dog's genes will have homozygous genes (i.e. the same genes).
Students rotate around the room at stations and randomly choose two alleles from a pile of laminated letters.
(B) DNA sequence of mutated alleles from MSTN - mutant colonies.
Still, because they carry random combinations of alleles from the C57BL / 6 and 129 genetic backgrounds, they are more appropriate controls than are mice of either parental strain.
(F) The sequence of eight mutant alleles from quadruple - mutant colonies # 5, # 45 and # 79.
However, unlike the parent strains, F1 hybrids do not breed true: the F2 offspring produced by mating F1 mice all have a unique random mixture of alleles from both parental strains.
The new passenger pigeons (birds carrying a fully edited set of alleles from each parent) will form the first true generation of de-extinct passenger pigeons.
When Parham compared the HLA genes of people from different regions of the world with the Neanderthal and Denisovan HLAs, he found evidence that non-African humans picked up new alleles from the hominins they interbred with.
An allele which dominates early in the game has a very high probability of completely excluding the other allele from the population.
The woman's unborn child inherits one allele from its mother and one from its father, which gives it a 25 percent chance of getting two healthy alleles; a 50 percent chance of one faulty allele and one healthy; and a 25 percent chance of getting two mutated alleles that together would cause it to develop beta - thalassaemia, a potentially fatal blood disorder caused by low oxygen uptake.
So, if a gene lies within a gene - dense, low - recombination region, then this means that a much larger number of progeny from crosses must be examined to find those that derive from rare recombinational events that separate the desired new allele from undesirable forms of neighboring genes.
When they expressed a mutant allele from a human sample with CD2AP - associated NS, the renal damage remained unchanged.
129 / Sv was transferred to Martin Evans (Cambridge) who introduced the Gpic allele from a 101 strain background.
Male wing size increases by 45 % through cell size and cell number changes when the ws1 allele from N. giraulti is backcrossed into a N. vitripennis genetic background.
We then looked whether there were reads at these sites that carried the majority allele from 1,000 Genomes (Supplementary Note 2).
Our Embark dog has a 50 % chance of inheriting the allele from the mother.
This also means he has a 50 % chance of not inheriting this Corgi allele from his mom.
If two dogs are both heterozygous for furnishings, there is a 25 % chance that each offspring could get the non-furnishings allele from each parent and not display that trait.
NCL is an autosomal recessive inherited disease i.e. the disease develops in dogs, who inherit the mutated allele from both parents.

Not exact matches

Until recently, half of the human race died from infectious causes before adulthood, providing strong selective pressure for genetic alleles that enhance host defence but why are the genetic alleles that are most frequently associated with depression so common in the modern gene pool?
(2) The prevalence of the MTHFR A1298C associated 3 genotypes and A / C alleles in the recurrent miscarriage group did not differ significantly from the control.
During reproduction, humans inherit two working copies of most genes — one copy, or allele, from each parent.
Every gene in (almost) every cell of the body is present in two variants — so called alleles: one is deriving from the mother, the other one from the father.
Taking advantage of the handful of complete human genome sequences now available, the pair looked at how alleles — the two copies of each gene we inherit from our parents — differ within a genome.
Additional analysis of UK Biobank data from 112,338 people of European ancestry revealed that a specific form of rs9349379 known as the G allele, which was present in 36 % of these individuals, was associated with an increased risk of coronary artery disease.
The most parsimonious explanation is that these alleles represent the ancestral human condition, inherited by both Neandertals and modern humans in Africa from their common ancestor, Capra says.
They soon noticed a strange pattern: Stretches of chromosomes inherited from Neandertals also carried ancient alleles, or mutations, found in all the Africans they studied, including the Yoruba, Esan, and Mende peoples.
In the U.S., this behavioral division follows a genetic one: workers bearing two copies of one form, or allele, of the Gp - 9 gene live in nests governed by a single matriarch, whereas those that have one copy or a pair of a second allele take orders from a female oligarchy.
Molecular forces, such as low mutation rates or meiotic drive — in which certain alleles have an increased likelihood of being passed from one generation to the next — influence the rate of speciation.
For example, they revealed that most organisms have two copies of each gene, one from each parent, and that a gene comes in a variety of different forms, or alleles.
There are two types of alleles, called A and G. Among the people with at least one A allele, 80 % benefited from the drug, while only 62 % of those with 2 G alleles did well.
Everyone has two copies, or alleles, of the 2A receptor gene, one from each parent.
Each Pm3 allele in the four new lines displayed the same activity as in the parental line, which results in increased overall activity, since it came from two different gene variations.
Instead, spontaneously transformed cells arose from the heterozygotes at a low frequency, and the majority of these cells had amplified the mutant allele.
A gene consists of two parts, known as alleles, one inherited from each parent.
Around the world, innovative genomic - medicine programs capitalize on singular capabilities arising from local health care systems, cultural or political milieus, and unusual selected risk alleles or disease burdens.
Every person has two copies, or alleles, of each gene, inheriting one copy from each parent.
As a result, the H19 gene, which restricts growth, was no longer active while the Igf2 gene, which promotes cell division, was now expressed from both the paternal and the maternal allele.
For the current study, the Stowers researchers focused on a differentially imprinted control region, which drives the reciprocal expression of H19 from the maternal allele and Igf2 (Insulin growth factor 2) from the paternal allele.
With patented DNA chips and corporate backers, he is looking for alleles that distinguish healthy Finns from patients with a family history of heart disease.
In contrast, the allele's frequency in women and in people from Northern California did not vary with age, presumably because fewer in these groups smoked heavily and the allele did not affect their survival.
Initially the people who drank milk from cows had something unusual about them, but by chance the new allele improved the welfare of human beings on their way north.
«The effect of viral replicative capacity is just as big as, and independent from, the effect of well - studied protective HLA alleles, which influence whether someone is likely to become an «elite controller,»» says Daniel Claiborne, lead author and postdoctoral fellow.
To understand how the different alleles influence the immune response to vaccination, the researchers next looked in more detail at immune cells from 47 of the patients (34 had two major T alleles, and 13 had at least one minor G allele).
The downside is that someone with two copies of the allele suffers from sickle - cell anemia, an incurable blood disorder.
And when they pre-treated immune cells from vaccinated major allele carriers with a molecule that inhibits the receptor that is normally stimulated by IL - 28B, they saw a stronger antibody response after the cells were stimulated with influenza vaccine.
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